A study was conducted by Diabetes related medical professionals, under the protocols established by Diabetes in Control and Logic Nutrution of San Diago Ca. Results showed that the use of the Low glycemic and nutritional products supplied by Logic Nutrition lowered average A1c’s from 8.6% to 7.6%

This ninety day study conducted by a group of your peers showed these results in 36 patients.  

The patients were randomized to 3 Protocols and were evaluated monthly.  

Patients varied from diet controlled to insulin dependent and age varied form 23 to 71 years old.  

It is interesting to note that although there was an overall drop in average A1c by 1%, the males in the group had an average decrease of 1.4% and both males and females who were in Protocol 3 had an average decrease of 1.3%

Title: The effect of Low Glycemic Foods on Blood Glucose in niddm and iddm patients.

Authors: Joffe, DJ editor@diabetesincontrol.com; Freed, SH, publisher@diabetesincontrol.com 

Source Diabetes in Control On Line Newsletter, Issue 106(1): 5 June 2002 

Abstract: 

Introduction

The low glycemic nutrition program incorporates the use of low glycemic carbohydrates that help stabilize blood sugar levels, reduce body fat and insulin resistance. The program eliminates high glycemic carbohydrates, over eating of protein and fat, all of which help create blood sugar spikes and the resultant insulin response. 

The 50-25-25 ratio of this Program purports to promote increased energy, balance, fat burning, recovery, mental clarity and hormonal function. 

In addition the program reduces total carbohydrates. Too many carbohydrates can spike your blood sugar, leading to increased fat storage, and pancreatic insulin response that can over time create hyperinsulinemia and insulin resistance which can increase your risk for cardiovascular disease. 

Too few carbohydrates deplete your energy and have a catabolic muscle wasting effect. Too much protein puts a strain on the kidneys and increases acidity levels in the body, while too little protein depletes brain, liver, organ and muscle tissue. The wrong type of fat can be damaging to your cells, while the right type of fat not only builds a healthy cell wall, but also increases the metabolism while optimizing hormonal function. 

The goal of the Program is to maximize the body's muscle functions and minimize and possibly reverse insulin resistance. This program can possibly be beta cell sparing by reducing the workload on the pancreas. 

The Program incorporates a low glycemic, nutrient dense, balanced approach to eating and supplementing. The program provided a meal plan that introduces foods and supplements in the specific 50-25-25 ratio of low glycemic carbohydrates, high quality protein, and essential fats. 

TRIAL DESIGN:  

60 diabetes patients were supplied with a complete nutritional program with a meal plan and 2 of the 5 meals a day.  These 2 meals will consist of 1 great tasting bar and 1 shake.  They will also be supplied with vitamin and mineral supplements.  The Study lasted for 90 days. The educator and patient were supplied with a brief manual and CD explaining the program, fat calibers for the educator and a help desk was available for any questions from educators or patients.                       

The participants were divided into 3 groups:

1. Individual meal plans + meal replacement bars* + shakes*
2. Individual meal plans + meal replacement bars* + shakes* + adaptapower *
3. Individual meal plans + meal replacement bars + shakes + adaptapower* + msm* + efas* + am/pm multi vitamin-mineral-herbs*

The following parameters were to be measured in the beginning and after 90 days

1. Hemoglobin A₁c
2. Blood Pressure
3. Body Weight
4. Cholesterol Levels

These parameters were to be averaged from daily self-testing results provided by the patients on a monthly basis.

1. Fasting Blood Glucose
2. PostPrandial Blood Glucose

In addition an exercise routine of at least 30 minutes daily at 60% of the maximum heart rate for at least 3 to 5 days a week was required and exercise time was recorded 

If above levels are improved with the Logic Nutrition Program^®, we will conclude that this treatment may add incremental benefit in diabetic patients.   

Objective:

The prevalence of diabetes has increased dramatically in recent years¹.    The purpose of this work was to investigate the acute effects of  switching to a low glycemic portion controlled diet and adding selected nutritional products in regards to it’s glucose lowering thereby reducing the HbA1c and therefore the complications from diabetes.   

By reducing the HbA1c (Average Blood Glucose) 1%, the DCCT² study showed Type 1 diabetics could reduce the complications of Retinopathy by 38%, Nephropathy by 28% Neuropathy by 35%. The UKPDS³ showed that reducing the HbA1c in Type 2 diabetics by 0.9% could reduce any diabetic end point by 12%, reduce any Microvascular end point by 25%, reduce MI by 16%, reduce Retinopathy by 21% and reduce microalbuminurea at 12 years by 34%.

The UKPDS also showed that Postprandial (blood glucose 1-2 hours after eating) glucose is a better indicator of glycemic control than fasting glucose levels⁴. Treatment of postprandial hyperglycemia is critical to achieving optimal outcomes in type 2 diabetes⁵. 

Methods:

36 of the original 60 participants completed the study. They were divided as follows.

12 – protocol  1; 11 – protocol  2; 13 – protocol 3

17 males; 19 females. Of these 12 were insulin dependent and 3 used the pump.

Their pre-study average fasting glucose (159 mg/dl) and postprandial blood glucose (185 mg/dl), and a base HbA1c (8.6) were taken.  Patients were instructed to follow the eating and exercise program as directed, in protocols 2 and 3 the patients took nutritional also  They continued to monitor fasting and postprandial blood glucose through the study period. At the conclusion of the 90-day period, their levels were measured. 

Results: 

36 of the original 60 participants completed the study. This represents a 40% drop out rate. Although this may seem high, one must remember that there was no financial renumeration for the participants. Other reasons for participants dropping out or being excluded, included, failure to monitor, gastric distress, family illness, relocation and failure to comply with meal plan. 

After 90 days on the Logic Nutrition Program the mean daily preprandial plasma glucose concentrations were 19 percent lower (154 vs. 124 mg/dl). The Logic Nutrition Program   also lowered the 2-hour postprandial plasma glucose concentrations, by 16 percent (186 vs. 155 mg/dl).  Logic Nutrition Program lowered HbA1c from 8.6% to 7.6% (1.0% decrease).

In addition The Logic Nutrition Program improved Total Cholesterol by 11%, HDL by 14% and Average Body Weight decreased by 15.8 lbs.

While all patients experienced a positive result, the participants in Protocol 3 experienced the most benefit from the program. In this group the mean daily preprandial plasma glucose concentrations were 29 percent lower. The Logic Nutrition Program also lowered the 2-hour postprandial plasma glucose concentrations, by 21 percent, and lowered HbA1c from 8.5 to 7.2% (1.3% decrease).

Conclusions:

As can be seen from the data above, the use of The Logic Nutrition Program in all patients with diabetes has a positive result. In addition the use of The Logic Nutrition Program in patients with the poorest control is even more critical. It appears that the largest effect occurs from decrease of postprandial glucose levels, which is consistent with the mechanisms of action stated.  The Logic Nutrition Program appears to improve glycemic control in patients with a both type 1 and type 2 diabetes. Reducing pre-prandial and postprandial blood glucose significantly caused a decrease of HbA1c, therefore reducing the complications from diabetes. ^2,3,4,5  

1-Beckles GLA et al. Diabetes Care. 1998;21:1432-1438.American Diabetes Association. Diabetes Care. 1998;21(Suppl 2).Colwell JA. Ann Intern Med. 1996;124(1pt2):131-135.Abraira C et al. Diabetes Care. 1992;15:1560-1571.Klein R et al. Am J Epidemiol. 1987;126:415-428.Cowie CC et al. Diabetes in America. 2^nd ed.vol. 44, November ol. 44, November, References

2- The New England Journal of Medicine -- September 30, 1993 -- Vol. 329, No. 14-DCCT research group, Diabetes 95;44:969-983;

3- Hawaii Med J 2000 Jul;59(7):295-8, 313; BMJ. 2000 Aug 12;321(7258):405-12.

4. Harris et al. Diabetes Care. 1994.

5- De Veciana et al. N Engl J Med. 1995;333:1239 

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