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Practical Diabetes Care, 3rd Ed., Excerpt #23: Diabetic Neuropathy Part 3 of 5

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David Levy, MD, FRCP      Charcot neuroarthropathy Charcot neuroarthropathy is a serious and poorly understood condition associated with rapid destruction of bones and joints and resulting in bone fragmentation. It occurs only in patients with advanced sensory and autonomic neuropathy, and is characteristic of long-duration type 1 diabetes with other microvascular complications, …

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Practical Diabetes Care, 3rd Ed., Excerpt #22: Diabetic Neuropathy Part 2 of 5

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David Levy, MD, FRCP      Foot ulceration The ulcerated, infected and possibly gangrenous foot is a common reason for hospital admission. Anatomically, diabetic foot ulceration is restricted to the region distal to the ankle; proximal lesions are more likely ischemic, vasculitic, venous, or to have another underlying cause. Most ulcers are predominantly …

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Practical Diabetes Care, 3rd Ed., Excerpt #21: Diabetic Neuropathy Part 1 of 5

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David Levy, MD, FRCP      Introduction The devastating consequences of diabetic neuropathy are seen every day both in hospital – more bed days are taken up with the consequences of diabetic foot ulceration than any other diabetic complication – and in primary care, where sensory symptoms, especially pain, and autonomic neuropathy, especially …

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Do Supplements Help Diabetes Vision?

Protection of visual function may signal disruption of mechanisms underlying diabetic retinopathy (DR)… This was a 6-month randomized, controlled clinical trial of patients with type 1 and type 2 diabetes with no retinopathy or mild to moderate non-proliferative retinopathy assigned to twice-daily consumption of placebo or a novel, multi-component formula …

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No Association Between Sulfonylurea Use and Cardiovascular Mortality

Sulfonylureas not associated with increased cardiovascular mortality, myocardial infarction and stroke in a meta-analysis of 47 randomized clinical trials… Sulfonylureas are relatively inexpensive and are important therapeutic agents in type 2 diabetes management. However, they are not widely used due to safety concerns regarding hypoglycemia and weight gain. Furthermore, it …

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Early Detection of Type 2 Diabetes Reduces Death Caused by Cardiovascular Disease

Early detection and treatment of type 2 diabetes may be more beneficial than aggressive control of blood glucose, blood pressure and cholesterol… Screening to identify type 2 diabetes followed by early treatment could result in substantial health benefits, according to new research that combined large scale clinical observations and innovative …

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Skin Bacteria a Cause of Diabetes?

Toxin produced by Staphylococcus aureus (S. aureus), a common skin bacteria, caused glucose intolerance in rabbit cells… Bacteria and viruses have an obvious role in causing infectious diseases, but microbes have also been identified as the surprising cause of other illnesses, including cervical cancer (Human papilloma virus) and stomach ulcers …

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