Diabetes in Control Publisher Steve Freed and Dr. Richard Bergman discuss his ADA presentations — the relationship between diabetes and altitude, and the role of kidneys in diabetes research. Steve also asks why the degredation of insulin in the liver is important in the pathogenesis of diabetes. Dr. Bergman is the founder and director of Diabetes and Obesity Research Institute, Biomedical Sciences at Cedars-Sinai in Los Angeles. He introduced the use of engineering principles to understand the pathogenesis of diabetes.
Read More »Mortality Among Persons with Type 2 Diabetes
Risks of death varied depending on age, glycemic control and renal complications.
Read More »Biomarkers of Major Adverse Outcomes in Diabetes
Recent study suggests that compelling biomarkers may predict major adverse outcomes, including death, in diabetes.
Read More »Finerenone Improves Albuminuria in Diabetic Nephropathy Patients
Mineralocorticoid receptor antagonists (MRAs) are often used with a renin-angiotensin system (RAS) blocker to further reduce proteinuria in patients with CKD. However, eplerenone and spironolactone increase the risk of hyperkalemia in these patients. Finerenone (BAY94-8862) is a new nonsteroidal MRA that has better receptor selectivity than spironolactone, associating with lower …
Read More »The Relationship Between Renal and Retinal Disorder in Type 2 Diabetes
Researchers study retinopathy as possible indicator of nephropathy… The number of diabetes mellitus cases is on the rise while the incidence of end-stage kidney disease from diabetes has decreased over the years. However, diabetes remains the main cause of end-stage kidney disease in the United States and other countries. There …
Read More »Practical Diabetes Care, 3rd Ed., Excerpt #24: Diabetic Neuropathy Part 4 of 5
David Levy, MD, FRCP Mononeuropathies and other focal syndromes Peripheral mononeuropathies Upper limb Carpal tunnel syndrome (median nerve) Carpal tunnel syndrome is very common (remember the association with primary hypothyroidism, especially in type 1 diabetes) and may present with atypical symptoms, as it is often superimposed on diabetic polyneuropathy. Consider it …
Read More »Paolo Fiorina, MD, PhD, Part 2: Factors in Stem Cell Therapy Cure Success
Dr. Paolo Fiorina talks about the process of stem cell therapy and how the researchers have found a way to use a patient’s own bone marrow stem cells. This also prevents an autoimmune response attacking the cells. Dr. Fiorina discusses how he would like to start fully testing this new …
Read More »Paolo Fiorina, MD, PhD, Part 1: Immunotherapy, Stem Cells, and Curing Type 1 Diabetes
Dr. Paolo Fiorina explains how, after 30 years of research into the potential of stem cell therapy and immunotherapy for curing type 1 diabetes, new developments in these fields are offering genuine hope for the first time. In a recent study with about 60 type 1 patients, significant progress was …
Read More »Walking Two Minutes Per Hour Extra Each Day Prolongs Life
Trading 2 minutes/hour of sedentary activity with light-intensity activity was linked to 33% lower mortality in the general population and 41% lower mortality in those with chronic kidney disease (CKD)… Numerous studies have shown that sitting for extended periods of time each day leads to increased risk for early death, …
Read More »Practical Diabetes Care, 3rd Ed., Excerpt #14: Diabetic Renal Disease Part 3 of 5
David Levy, MD, FRCP Management of diabetic nephropathy Investigations Mid-stream urine if leucocytes on routine urinalysis. Renal tract ultrasound scan: a. Normal renal length is about 11 cm, correlating weakly with height and BMI; it is about 10 cm in South Asian and oriental subjects. Kidneys are large in the poorly …
Read More »