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Sleep Duration and Risk of Premature Death in Patients with T2DM

Jan 5, 2021
Editor: Steve Freed, R.PH., CDE

Author: Louise Brown, PharmD Candidate, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Both sleep deprivation and excessive sleep duration may be independent risk factors for premature death in patients with T2DM.  

According to the National Sleep Foundation (NSF), the recommended amount of daily sleep varies depending on age and health status. The NSF recommends 7-9 hours of sleep for adults 18-64 and 7-8 hours for adults ≥65. Sleep duration has been identified as a risk factor for impaired glycemic control. Too much or too little sleep can negatively impact glucose control in patients with T2DM. In general, these observations occurred in studies of individuals who slept on average four and a half to six hours per night. Long term sleep deviations of <5 hours/day or >9 hours/day have been associated with increased mortality and cardiovascular disease. Multiple explanations have been proposed to explain this relationship between sleep duration and glycemic control....


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