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SGLT-2 Inhibitors’ Association with Fournier Gangrene

Dec 10, 2019
 
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Maya Rudolph, Florida A&M University, College of Pharmacy & Pharmaceutical Sciences, PharmD Candidate

While rare, Fournier gangrene infections can worsen rapidly and have serious consequences. 

Fournier gangrene is a rare, life-threatening bacterial infection of the skin that involves the tissues, surrounding muscles, nerves, and blood vessels of the external genitalia, perianal region, and perineum (the area between the anus and scrotum for men; between the anus and vulva for women). Bacteria, spreading from a skin wound or injury, destroys the tissue leading to a necrotizing infection....

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