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Reversing the Metabolic Syndrome (MetS) & Preventing Type 2 Diabetes

Oct 26, 2019
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Marian Ayad, BPharm, PharmD candidate, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Metabolic syndrome (MetS) can be defined as a set of interconnected, physiological, biochemical, clinical, and metabolic factors that increase risk of CV disease, type 2 diabetes, and all-cause mortality. A few characteristics of MetS include high BP, high blood glucose, and excess body fat around the waist. Carbohydrate intake stimulates insulin secretion, which in turn stimulates fat storage and inhibits adipose tissue lipolysis and fatty acid oxidation and increases hyperinsulinemia, which is highly correlated with MetS. This indicates that a high carbohydrate diet may play an important role in the pathogenesis of MetS....


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