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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #80: Insulin Actions In Vivo: Glucose Metabolism Part 6 of 9

Intravenous glucose: In the presence of euglycemia, insulin displays a potent suppressive action on hepatic glucose production, such that portal insulin concentrations of less than 100 mU L−1 abolish glucose entry into the circulation. Figure 14.7 shows a typical time course for endogenous glucose production following an acute increase in plasma insulin to levels of 60 – 70 mU L−1 in a healthy subject.

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