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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #82: Insulin Actions In Vivo: Glucose Metabolism Part 9 of 9

Oral glucose: At any point in time, the glycemic response to exogenous glucose is the balance between the rate at which glucose appears in the systemic circulation (from oral as well as endogenous sources) and the rate at which glucose is disposed of. Oral glucose appearance in the peripheral circulation depends on: (a) the rate at which the gastric contents are passed on to the small intestine; (b) the rate of intestinal glucose absorption; (c) the extent of gut glucose utilization; (d) the degree of hepatic glucose trapping; and (e) the dynamics of glucose transfer through gut, liver, and posthepatic circulation on to the right heart.

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A1c for Metformin

At what A1c level would you recommend the use of metformin? 1. 5.6% 2. 5.7 – 5.9% 3. 6.0% 4. 6.1 – 6.2% 5. 6.3 – 6.4% 6. 6.5 – 7% Follow the link to share your response.

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