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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #69: Regulation of Glucose Metabolism in Liver Part 5 of 11


Transcriptional regulation of gluconeogenesis: The gradual shift from the fed-to-fasted state is followed closely by hormonal regulation of genes encoding PEPCK, fructose-1,6-bisphosphatase, and the glucose-6-phosphatase catalytic subunit. The transcriptional regulation of these genes remains a developing research area and its many emerging nuances cannot be completely covered here.

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