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RESOURCES

What is the Most Ineffective Medication?

As we know, the most ineffective medication is the one needed but never taken. There are many reasons our patients don’t take prescription medicines, but a biggy is the cost. If a medicine is too expensive, the patient will not fill the prescription, therefore won’t take it. For example, when ordering an SGLT-2 and/or GLP-1, each can cost hundreds or more for a month’s prescription. Some are covered for both. Some are covered for one brand, but not the other.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #79: Insulin Actions In Vivo: Glucose Metabolism Part 5 of 9

The fed state is the absorptive period between meals. Carbohydrates are normally mixed with lipids and protein in the diet and make up 40 – 60% of the caloric content. Absorption of dietary carbohydrates is influenced by their chemical form (refined sugars or complex carbohydrates) and by other components of food. Furthermore, disposition of dietary carbohydrate is indirectly affected by fats and protein to the extent that these latter (i) compete with glucose as substrates, and (ii) interfere with glucoregulatory hormones by altering insulin secretion.

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