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Hypertriglyceridemia Strategies

Which of the following is a recognized strategy when considering diet and exercise in the management of hypertriglyceridemia?

A. Individuals should consume 45% of calories as fat, with saturated fat reduced to approximately 20% of calories.
B. Restricting simple carbohydrates and increasing dietary fiber are ineffective for lowering triglycerides.
C. Exercise has minimal impact on lowering triglyceride levels.
D. Progressive aerobic and toning exercise, weight loss, and dietary management can significantly lower triglyceride levels.

Follow the link for the answer.

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Considering Ethnicity

Do you consider ethnicity when determining the best treatment options for your patients? Follow the link to see how you and your colleagues compare.

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Prevent Disasters By Using CGM

Man, 69 years of age, of Italian descent, “a numbers guy,” has type 2 diabetes, A1C 8.9%, taking a GLP-1 daily, and metformin 1,000mg twice daily. Blood pressure was managed, in target range of ~110-120/70-80, HR 76-82, weight-BMI 25.3. Had been on an SGLT-2, but developed DKA, so he can no longer take SGLT-2’s nor did he want to. Checked fasting glucose some mornings a week but not every day because he did not like to stick his finger. He really didn’t want to deal with his diabetes. Due to his recent illness, he was willing to try something new and different, especially since I told him it’s about numbers and he would not have to regularly stick his fingers.

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Judith Wylie-Rosett 2018 Complete Interview

Judith Wylie-Rosett, EdD, RD, is a professor at the Albert Einstein Medical Center and co-director of the New York Regional Center for Diabetes Translation Research in Bronx, NY. Dr. Wylie-Rosett’s research focuses on nutrition’s role in preventing and controlling chronic diseases—particularly diseases such as type 2 diabetes and heart disease in which obesity is an important risk factor.  She is associate editor of the journal Diabetes Care and author of The Complete Weight Loss Workbook. Dr. Wylie-Rosett has helped the American Diabetes Association and American Heart Association develop nutrition-related recommendations and position statements.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #153: Monogenic Disorders of the Beta Cell Part 3

Glucokinase MODY: Glucokinase catalyzes the phosphorylation of glucose to glucose-6-phosphate. Its unique kinetic properties result in the rate of glucose phosphorylation being proportional to the physiologic glucose concentration. This means that the beta cell and hepatocyte can respond appropriately to fluctuations in the degree of glycemia. In the pancreatic beta cell, glucokinase acts as “the glucose sensor” ensuring insulin release is appropriate to the blood glucose concentration.

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