Friday , May 25 2018
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Treating Type 2

For a patient with type 2 who has an A1c of 8% and is on metformin, has tried diet change and exercise, and is 25 pounds overweight, which of the following would you prefer: GLP-1, SGLT-2, or something else? Follow the link to share your opinion.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #123: The Insulin Resistance Syndrome Part 4

The foregoing observations have detailed the best established risk factors associated with insulin resistance as well some novel emerging risk factors as additionally detailed in Table 23.2, including nutritional measures such as Vitamin D. These are not comprehensive but rather a selection of emerging pathways of interest. Clearly, future research should increasingly harness genetics as well as observational data to better determine causal risk pathways. Similarly, further data are needed to better determine the extent to which insulin resistance is, or is not, linked to cardiovascular risk.

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Counterpoint: The Pros and Cons of AI-based “Diagnosis” of Diabetic Retinopathy

By A. Paul Chous, MA, OD, FAAO, CDE

The FDA just gave first approval to an artificial intelligence (AI) algorithm for the detection of diabetic retinopathy in the offices of non-ophthalmic health care practitioners. Dubbed the IDx-DR (IDx, LLC, Coralville, Iowa), and paired with a Topcon NW400 non-mydriatic retinal camera, captured images are sent to a cloud-based server that utilizes the IDx-DR software and a ‘deep learning’ algorithm to detect retinal findings consistent with diabetic retinopathy based on autonomous comparison with a large dataset of representative fundus images.

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