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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #153: Monogenic Disorders of the Beta Cell Part 3

Glucokinase MODY: Glucokinase catalyzes the phosphorylation of glucose to glucose-6-phosphate. Its unique kinetic properties result in the rate of glucose phosphorylation being proportional to the physiologic glucose concentration. This means that the beta cell and hepatocyte can respond appropriately to fluctuations in the degree of glycemia. In the pancreatic beta cell, glucokinase acts as “the glucose sensor” ensuring insulin release is appropriate to the blood glucose concentration.

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Pumps vs. Daily Injections: What’s the Future of Insulin Delivery?

Diabetes in Control readers are being asked to participate in exclusive research that will provide new insights into what you think about insulin pumps and daily injections. Whether you’re a patient, a patient family member, medical professional or diabetes educator, we need to hear from you. Please take a few moments to take our survey and help our research. The survey takes only about 3 minutes, is completely anonymous, and lets you make your voice heard in analysis that can potentially influence the future of insulin delivery research and development.

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