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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #88: Measuring Insulin Action In Vivo


Insulin sensitivity based upon the OGTT: The previous discussion suggests that “quick and dirty” indices from fasting values may not be accurate, and it is often true that laboratory procedures are impractical. Recently, it has been suggested that indices calculated from the OGTT may be useful for population studies. For decades the OGTT has been used as a screening test and a diagnostic tool for diabetes and IGT. It might be ideal if one could classify the state of carbohydrate tolerance and simultaneously measure insulin sensitivity and beta-cell function.

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Minimizing Side Effects

Test Your Knowledge

Your patient has been newly diagnosed with type 2 diabetes (A1C 7.7%) and you have prescribed metformin. Metformin should be titrated to minimize which side effect? A. Rebound hyperglycemia B. Reactive hypoglycemia C. Weight gain D. Gastrointestinal-side effects Follow the link to see the answer.

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BG Monitoring Recommendations


How often do you recommend to your type 2 patients who are not on insulin to monitor their blood sugars daily? 1. Once a day 2. Twice a day 3. More than twice a day 4. Once a week or Less than daily Follow the link to share your response.

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