Clinical Presentations

In this week's Homerun Slides,  the accuracy of CGMs and the benefit for insulin-using patients.

In this week's Homerun Slides, the effectiveness of the CGM to reduce A1C and hypoglycemia.

In the conclusion of this week's Homerun Slides, the clinical performance of the Eversense CGM System.

In this week's Homerun Slides, understanding the sensor procedure for the Eversense CGM.

In this week's Homerun Slides, explaining how the Eversense CGM System works.

In this week's Homerun Slides, we begin a review of the new Eversense CGM system.

In this week's Homerun Slides, the conclusion of the pathophysiology of type 1 diabetes with the side effects of insulin and treating hypoglycemia.

In this week's Homerun Slides, the general concept of insulin pump therapy and CGM patterns.

In this week's Homerun Slides, insulin initiation and a comparison of pharmacokinetic and pharmacodynamic insulins.

Cellular mechanisms of insulin resistance: The cellular events via which insulin initiates its stimulatory effect on glucose metabolism start with binding of the hormone to specific receptors that are present on the cell surface of all insulin target tissues. After insulin has bound to and activated its receptor, “second messengers” are generated and these second messengers activate a cascade of phosphorylation-dephosphorylation reactions that result in stimulation of intracellular glucose metabolism. The first step in glucose utilization involves activation of the glucose transport system, leading to glucose influx into insulin target tissues, primarily muscle. The free glucose, which has entered the cell, subsequently is metabolized by a series of enzymatic steps that are under the control of insulin. Of these, the most important are glucose phosphorylation (catalyzed by hexokinase), glycogen synthase (which controls glycogen synthesis), and phosphofructokinase (PFK) and PDH (which regulate glycolysis and glucose oxidation, respectively).