Ramsi Ajjan John, who is a 61-year-old postman, presents to his GP with a 6-week history of increasing tiredness, polyuria and polydipsia. He has also noticed weight loss over the past 6 months (around 5 kg) and an irritating cough that seems to have coincided with him stopping smoking around …
Read More »ADA/JDRF Type 1 Diabetes Sourcebook, Excerpt #14: Beta-Cell Replacement Therapy, Part 1 of 2
Anne Peters, MD, and Lori Laffel, MD, MPH, Editors Jane Lee Chiang, MD, Managing Editor Andrew M. Posselt, MD, PhD, FACS, and Peter Stock, MD, PhD The goal of curing type 1 diabetes (T1D) is best achieved with beta-cell replacement therapy because this allows physiologic blood glucose control. Currently, the …
Read More »Joslin’s Diabetes Deskbook, Updated 2nd Ed., Excerpt #37: Psychological Issues in the Treatment of Diabetes, Part 2 of 3
Barbara J. Anderson, PhD, CDE and Abigail K. Mansfield Marcaccio, PhD The week’s excerpt answers the following questions: What is "Miscarried Helping"? What are the steps in preventing "Miscarried Helping"? How can you foster an open provider-patient relationship? What are the steps to preventing diabetes "burnout"? How can primary care …
Read More »ADA/JDRF Type 1 Diabetes Sourcebook, Excerpt #13: Setting Treatment Targets, Part 2 of 2
Anne Peters, MD, and Lori Laffel, MD, MPH, Editors Jane Lee Chiang, MD, Managing Editor Jane Lee Chiang, MD, and Stephen E. Gitelman, MD GUIDELINES Current guidelines for glycemic control from select organizations worldwide are shown in Table 6.4.19-22,62 Due to the special nature of T1D, only those guidelines that …
Read More »ADA/JDRF Type 1 Diabetes Sourcebook, Excerpt #12: Setting Treatment Targets, Part 1 of 2
Anne Peters, MD, and Lori Laffel, MD, MPH, Editors Jane Lee Chiang, MD, Managing Editor Jane Lee Chiang, MD, and Stephen E. Gitelman, MD INTRODUCTION The Diabetes Control and Complications Trial (DCCT)1 was a landmark medical study conducted by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). …
Read More »Diabetes Clinical Case Series, Excerpt #2, Endocrinology and Diabetes
Ramsi Ajjan Andrea is a 35-year old solicitor who presents with a 10-day history of constant palpitations, weakness, and irritability….
Read More »ADA/JDRF Type 1 Diabetes Sourcebook, Excerpt # 11: Interdiction, Part 3 of 3
Anne Peters, MD, and Lori Laffel, MD, MPH, Editors Jane Lee Chiang, MD, Managing Editor Prevention of β-cell Destruction and Preservation for Those with Existing Type 1 Diabetes Jane Lee Chiang, MD, and Stephen E. Gitelman, MD Role of Regulatory T-cells In moving these studies from bedside back to bench, …
Read More »Joslin’s Diabetes Deskbook, Updated 2nd Ed., Excerpt #36: Psychological Issues in the Treatment of Diabetes, Part 1 of 3
Barbara J. Anderson, PhD, CDE and Abigail K. Mansfield Marcaccio, PhD This week’s excerpt answers the following questions: How do you screen patients for psychological issues at diagnosis of diabetes? When can you use the terms "a touch of sugar" and "borderline diabetes"? How important is it to address misconceptions …
Read More »ADA/JDRF Type 1 Diabetes Sourcebook, Excerpt #10: Interdiction, Part 2 of 3
Anne Peters, MD, and Lori Laffel, MD, MPH, Editors Jane Lee Chiang, MD, Managing Editor Interdiction: Prevention of Beta-cell Destruction and Preservation for Those with Existing Type 1 Diabetes Jane Lee Chiang, MD, and Stephen E. Gitelman, MD Anti-Inflammatory Agents European Nicotinamide Diabetes Intervention Trial (ENDIT). Like DPT-1, ENDIT represented …
Read More »Clinical Cases Uncovered: Diabetes and Endocrinology, Excerpt #1
Ramsi Ajjan This week we begin a new series of Clinical Text excerpts with a focus on case studies. Each case is presented as you would actually see it and the use of real-life experiences means the decisions and outcomes are factually based. Along the way to determining a diagnosis …
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