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Rhoda Cobin 2018 Complete Interview

Rhoda H. Cobin, MD, MACE is Clinical Professor of Medicine at the Ichan School of Medicine at Mount Sinai NYC. She is a founding board member of AACE, served as its president and the president of the American College of Endocrinology. Dr. Cobin's academic interests include reproductive endocrinology, thyroid disease and thyroid cancer, and diabetes. She was one of the chairs for the production of AACe's Disease State Clincial Review : Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome. She and AACE have particularly been concerned for over a decade with increasing awareness of the significant cardiometabolic consequences of PCOS.

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International Textbook of Diabetes Mellitus, 4th Ed., Excerpt #144: The Genetics of Type 2 Diabetes Part 6

Gene–gene and gene–environment interactions: Gene–gene interactions, or epistasis, have been suggested as a possible explanation for difficulties in replicating genetic association in complex diseases. The standard statistical methods used in association studies are usually limited to analysis of single marker effects and thereby do not account for interactions between markers. Previous attempts to study epistasis in complex diseases have focused on interactions between candidate regions. However, the recent abundance of GWAS data has made a comprehensive search across the genome more feasible.

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Rhoda Cobin 2018 Transcript

In this Exclusive Interview transcript, Rhoda Cobin talks with Diabetes in Control Medical Editor Joy Pape during the AACE 2018 convention in Boston about the association between diabetes and PCOS, the genetic component of PCOS, and the syndrome's long-term health implications.

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