Thursday , December 14 2017
Home / Resources / Test Your Knowledge / Question #842

Question #842

Based upon a meta-analysis of cardiovascular outcomes in type 2 diabetes studies, findings suggest that a 15% relative risk reduction in nonfatal myocardial infarcts is associated with an A1C reduction of approximately:

Correct

Answer: 2. 1.0%

Educational Critique: A meta-analysis of cardiac outcomes in the Action to Control Cardiovascular Risk in Diabetes (ACCORD), Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) and Veteran Affairs Diabetes Trial (VADT) found every approximate 1% A1C reduction was positively correlated with a 15% relative risk reduction for myocardial infarct. The A1C benefits did not extend to stroke or all-cause mortality.

BMJ  v.321(7258); 2000 Aug 12 PMC27454

Incorrect