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Question #823

Mar 5, 2016

Mrs. Hunter is a 36-year-old African-American who comes to your office for her annual wellness exam. She is overweight (BMI 27 kg/m2), but is otherwise healthy. She jokes that she “just can’t seem to lose that extra baby weight” after giving birth 3 years ago. However, her daughter recently started preschool, so she has been able to go to her new gym several times per week. In fact, one of the added bonuses of her membership is the free, weekly nutrition and exercise support groups. In addition to her routine labs, you order an A1C, which comes back elevated at 7.1%. This measurement is confirmed several days later.

Based on Mrs. Hunter’s profile, what would a reasonable next step be?


Answer:  C. Encourage lifestyle modifications and do not initiate drug therapy at this time

Encourage lifestyle modifications and do not initiate drug therapy at this time. In general, it is reasonable to give patients who are already near target (A1C<7%) at time of diagnosis and are highly motivated to engage in lifestyle modifications a window of opportunity to engage in lifestyle modifications for a trial period of 3-6 months before embarking on pharmacotherapy. In select patients (highly motivated, newly diagnosed, long life expectancy, no significant comorbidities), more stringent A1C targets (<6.5%) may be considered as long as they can be achieved without adverse treatment effects or significant hypoglycemia. Reference(s):

Inzucchi S, et al. Management of hyperglycemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2012; 35(6):1364-1379.