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Philipp Scherer, PhD: How does lipotoxicity relate to type 2 diabetes?

Mar 22, 2014
 

Philipp_Scherer

Dr. Philipp Scherer talks about how lipotoxicity is critically important in diabetes because of its direct negative effect on cells, especially beta cells. In fact, lipotoxicity may be at the core of beta cell failure; a lot of evidence associated with insulin resistance and inflammation seem to be related….

 

More videos with Dr. Scherer:

Philipp Scherer, Ph.D., Professor, UT Southwestern, Introduction
Q1: Role of Adipose Tissue in Metabolic Health
Q2: Is there such a thing as “healthy” obesity?
Q3: Effects of Lipotoxicity on Beta Cells
Q5: How does lipotoxicity affect CV disease in type 2 diabetes?
Q6: What is the role of mitochondria in brown fat?
Q7: Difference between “healthy” obese and non-healthy obese
Q8: Genetics of Metabolically Healthy Obese Individuals
Q9: Potential pharmacological innovations in metabolism control
Q10: Will we invent an “exercise pill”?

Dr. Philipp Scherer is Professor and Director of the Touchstone Diabetes Center at the University of Texas Southwestern Medical Center in Dallas. Dr. Scherer received his Ph.D. degree from the University of Basel, Switzerland working on mitochondrial biogenesis, followed by post-doctoral time in the Whitehead Institute at the Massachusetts Institute of Technology. In 1997, he joined the faculty of the Albert Einstein College of Medicine where he was a Professor for Cell Biology and Medicine until his move to Dallas in early 2007. Current efforts in his laboratory are focused on the identification and physiological characterization of novel proteins that serve as potential links between the adipocyte and the processes of whole body energy homeostasis, inflammation and cancer.