Diabetes In Control. A free weekly diabetes newsletter for Medical Professionals. News and information for Medical Professionals.
Letter from the Editor
On the Doximity website there has been a lot of chatter amongst medical professionals on the idea of a once daily “super pill” for everyone, to prevent diabetes and CVD. The combination for this pill often changes, but an ACE-I and a statin seem to always be in the mix. Although these meds, along with low dose ASA and metformin, seem to be the best choices, our intern, Nadeen Ayad, BCPS, PharmD candidate, Skaggs School of Pharmacy, University of Colorado, has put together a group of studies that looks at which meds would actually make the best combo for diabetes prevention. Her results are based on over 3.7 million patients. I bet you money the results will flat out surprise you.
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We can make a difference!
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Dave Joffe
Editor-in-chief
Newsflash: FDA Approves New Dexcom CGM
The FDA on Tuesday approved the use of a professional continuous glucose monitoring system from Dexcom which can be used blinded or unblinded.
TOP STORIES — Diabetes News and Research
Pharmacological interventions may have a role to play in preventing progression to type 2 diabetes, but are they more important than lifestyle factors?
A new study looks at the growing use of non-nutritive sweeteners and if they may cause, or help prevent, type 2 diabetes.
Is the CAC score a reliable tool in assessing cardio risk in patients with type 1 diabetes?
Did You Know: That Coffee Can Save Your Life
In a recent published meta-analysis in the European Journal of Epidemiology researchers found that, if you want to live a long and healthy life, just drink a few cups of coffee every day. That was the final analysis that people who drink 2 to 4 cups of coffee a day have a reduced all-cause mortality and reduced cause-specific mortality compared with people who drink no coffee—even when factors such as age, weight, smoking, and drinking alcohol are considered.
Drinking about three to four cups of coffee a day can lower your risk of premature death. How much coffee must you drink to get the benefits? The researchers determined that the ideal amount is 3.5 cups of coffee per day to get the greatest risk reduction—15%—in all-cause mortality. For cardiovascular disease (CVD) mortality, 2.5 cups reduce risk the most, by 17%. And 2 cups per day is associated with the lowest relative risk in cancer mortality—4%—compared with drinking no coffee. The researchers found that you can stop at 3.5 cups a day, though. Drinking more coffee than this won’t increase your longevity any further. The link between lower mortality and coffee consumption even holds true no matter if it’s decaf or regular. This may be because coffee contains various antioxidant components such as caffeine, chlorogenic acid, melanoidins, cafestol, kahweol, and trigonelline, which may prevent oxidative damage. For this analysis, the authors reviewed 40 studies that included a total of 3,852,651 participants. Because they had many studies, the researchers were able to investigate associations between coffee consumption and all-cause mortality for a variety of factors, such as age, sex, geographic region, overweight status, alcohol consumption, and smoking status. But it turned out that most of these factors made no difference in coffee’s relation to reduced mortality.
Diabetes in Control gratefully acknowledges the assistance of the following pharmacy doctoral candidates in the preparation of this week’s newsletters:
Nadeen Ayad, BCPS, PharmD Candidate, Skaggs School of Pharmacy, University of Colorado
Usif Darwish, PharmD Candidate, Florida A&M University, College of Pharmacy & Pharmaceutical Sciences
Keri Hames, PharmD Candidate, Florida A&M University, College of Pharmacy & Pharmaceutical Sciences
Joel John, Pharm.D. Candidate, Florida A&M University, College of Pharmacy & Pharmaceutical Sciences
Nour Salhab, Pharm.D. Candidate, USF College of Pharmacy
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