Drug Name: Novolog Mix 70/30

The following information is obtained from various newswires, published medical journal articles, and medical conference presentations.

Company: Novo Nordisk
Approval Status: Approved November 2001
Treatment for: Diabetes

General Information

Novolog Mix is an insulin analog premix containing 30% rapid-acting insulin aspart and 70% that has been modified into a long-acting formulation. It has been approved in a subcutaneous injection formulation, for the control of hyperglycemia. Hyperglycemia is an abnormally increased content of sugar in the blood.

Diabetes is a chronic disease that requires a combination of professional medical care and self-management through strict attention to diet, self-medication, and frequent monitoring one's blood sugar level.

Clinical Results

Approval of NovoLog Mix 70/30 is based on results from clinical trials evaluating glycaemic control in subjects with type 1 and 2 diabetes.

Side Effects

Adverse events associated with the use of human insulin therapy include (but are not limited to) the following:

• Injection site reaction
• Lipodystrophy
• Pruritus
• Rash
• Hypoglycemia

Mechanism of Action

NovoLog Mix 70/30 regulates glucose metabolism. Insulins, including Novolog Mix, bind to insulin receptors on muscle and fat cells. They lower blood glucose by facilitating the cellular uptake of glucose, while simultaneously inhibiting the output of glucose from the liver.  For more info: www.novonordisk.com

 

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