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More on Coffee and T2DM

Consumption of coffee and caffeine can help reduce type 2 diabetes mellitus incidence…. 

The prevalence of diabetes has increased from 8.2% in 1980 to 2008 in men and from 7.5 to 9.2% in women. The number of people with diabetes has increased from 153 million in 1980 to 347 million in 2008. Prevention of diabetes through weight control, physical activity and improved diet quality has been crucial. Researchers have identified components in coffee that may affect the development of diabetes.  

Researchers conducted a meta-analysis of prospective studies by using the databases of PubMed and EMBASE. These studies had to have the following criteria: a prospective design, exposure to either coffee or caffeine, T2DM as the outcome of interest, multivariate-adjusted relative risk (RR) with 95% confidence interval and analysis for each category that was examined.

The results from 26 articles showed the RR of T2DM was 0.71 for the highest level of coffee intake. In women, there was a stronger association of coffee intake and the incidence of T2DM than there was in men. Also, a stronger association of coffee intake and the incidence of T2DM were found in non-smokers and subjects with BMI <25 kg/m2. When looking at the dose-response analysis, the incidence of T2DM was decreased by 12% for every 2 cups/day increment in coffee intake, 11% with decaffeinated coffee and 14% for every 200mg/day increment in caffeine intake.

With the findings in the prospective studies, intake of coffee and caffeine may significantly have an inverse association with T2DM incidence.

Practice Pearls:

  • The number of people with diabetes has increased from 153 million in 1980 to 347 million in 2008.
  • Incidences of T2DM were decreased by 12% for every 2 cups/day increment in coffee intake.
  • Smoking was found to have a positive association with coffee consumption.

Springer Nov, 2013