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Lifestyle Interventions Result in Modest Improvements in Type 2 Diabetes

Lifestyle-based weight loss intervention trials achieve modest reductions in weight and glycated hemoglobin (HbA1c) levels, according to a meta-analysis. From six studies comparing lifestyle intervention with usual care, the researchers found the pooled effect on weight (5,795 patients) to be −3.33 kg, and −0.29% on HbA1c (5,784 patients), with both findings weakened in sensitivity analyses. From all 10 lifestyle intervention groups, the pooled within-group effect on weight (3,063 patients) was −5.33 kg, which was also weakened in sensitivity analyses. — Diabetes, Obesity, & Metabolism, DOI: 10.1111/dom.12430