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June 2020 Briefing – Diabetes & Endocrinology

Jul 1, 2020
 

Here are what the editors at HealthDay consider to be the most important developments in Diabetes & Endocrinology for June 2020. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Global Burden of Thyroid Cancer Is Increasing

TUESDAY, June 30, 2020 (HealthDay News) — There is an increasing global burden of thyroid cancer, according to a study published online June 26 in JAMA Network Open.

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Comparative Effectiveness of Treatments Explored in T2DM

TUESDAY, June 30, 2020 (HealthDay News) — For patients with type 2 diabetes at low cardiovascular risk, there are no differences in vascular outcomes between treatments, according to research published online June 30 in the Annals of Internal Medicine.

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Editorial (subscription or payment may be required)

Government E-Cigarette Restrictions on Marketing Lower Use

MONDAY, June 29, 2020 (HealthDay News) — Comprehensive provincial restrictions on electronic cigarette marketing are associated with lower levels of exposure to marketing and lower prevalence of e-cigarette use, according to a Canadian study published online June 29 in Pediatrics.

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Trump Administration Asks Supreme Court to Overturn Affordable Care Act

FRIDAY, June 26, 2020 (HealthDay News) — The Trump administration has asked the Supreme Court to overturn the Affordable Care Act (ACA).

Washington Post Article

CDC Updates List of Who Is at Highest Risk for COVID-19

FRIDAY, June 26, 2020 (HealthDay News) — The list of conditions that put people at risk for severe COVID-19 illness has been expanded by the U.S. Centers for Disease Control and Prevention.

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Women Have More Brain Changes Related to Alzheimer Disease

FRIDAY, June 26, 2020 (HealthDay News) — Cognitively normal women have increased Alzheimer disease endophenotype, with higher β-amyloid deposition, lower glucose metabolism, and lower gray and white matter volumes, according to a study published online June 24 in Neurology.

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Heart Failure Ups Risk of Death in Patients With New T2DM

FRIDAY, June 26, 2020 (HealthDay News) — For patients with newly diagnosed type 2 diabetes (T2D), heart failure development is associated with increased five-year absolute and relative risks of death, according to a study published online June 23 in Circulation: Cardiovascular Quality and Outcomes.

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Administrative Data Predict Mortality With Diabetes

THURSDAY, June 25, 2020 (HealthDay News) — Factors readily available in administrative data can predict five- and 10-year mortality in older adults with diabetes, according to a study published online June 19 in Diabetes Care.

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Metabolic Syndrome Up in Young Adults in the United States

THURSDAY, June 25, 2020 (HealthDay News) — The prevalence of metabolic syndrome among young adults in the United States is rising, according to a research letter published in the June 23/30 issue of the Journal of the American Medical Association.

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Allopurinol Does Not Affect eGFR in Chronic Kidney Disease

THURSDAY, June 25, 2020 (HealthDay News) — Allopurinol does not affect estimated glomerular filtration rate (eGFR) in patients with chronic kidney disease and does not result in a clinically meaningful benefit in kidney outcomes from serum urate reduction among patients with type 1 diabetes and early-to-moderate diabetic kidney disease, according to two studies published in the June 25 issue of the New England Journal of Medicine.

Abstract/Full Text – Badve (subscription or payment may be required)

Abstract/Full Text – Doria (subscription or payment may be required)

Editorial (subscription or payment may be required)

Sex, Ethnic Differential Patterns of COVID-19 Unexplained

THURSDAY, June 25, 2020 (HealthDay News) — Sex and ethnicity differential patterns of COVID-19 positivity are not explained by cardiometabolic, socioeconomic, or behavioral factors, according to a study published online June 19 in the Journal of Public Health.

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Inhibition of Sclerostin May Increase Cardiovascular Risk

THURSDAY, June 25, 2020 (HealthDay News) — Inhibition of sclerostin with romosozumab may increase cardiovascular risk, according to research published in the June 24 issue of Science Translational Medicine.

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ED Use Down for MI, Stroke, Hyperglycemic Crisis in COVID-19

WEDNESDAY, June 24, 2020 (HealthDay News) — Following declaration of the COVID-19 pandemic as a national emergency, there was a decrease in visits to the emergency department for myocardial infarction (MI), stroke, and hyperglycemic crisis, according to research published in the June 22 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Odds of Pregnancy Decrease With Prolonged Embryo Storage

WEDNESDAY, June 24, 2020 (HealthDay News) — Prolonged storage of embryos after vitrification is associated with a reduced likelihood of biochemical pregnancy, clinical pregnancy, and live birth, according to a study published online June 23 in Human Reproduction.

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Patients With COVID-19 Mount Acute Cortisol Stress Response

WEDNESDAY, June 24, 2020 (HealthDay News) — Patients with COVID-19 mount a marked and appropriate acute cortisol stress response, according to a research letter published online June 19 in The Lancet Diabetes & Endocrinology.

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Older Age, Black Race, Diabetes Up Hospitalization in COVID-19

WEDNESDAY, June 24, 2020 (HealthDay News) — Characteristics that are independently associated with hospitalization for COVID-19 include older age, black race, and having diabetes mellitus, according to research published in the June 17 early-release issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.

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Subtypes, Genetic Links Identified for Polycystic Ovary Syndrome

TUESDAY, June 23, 2020 (HealthDay News) — Distinct subtypes of polycystic ovary syndrome (PCOS) with novel genetic associations have been identified, according to a study published online June 23 in PLOS Medicine.

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Safety Climate Perceptions Linked to Health Provider Stress

MONDAY, June 22, 2020 (HealthDay News) — Safety climate perceptions are associated with care practitioner-reported stress and job satisfaction, according to a study published in the May-June issue of the Journal of Healthcare Management.

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Adult T2DM Susceptibility May Be Identifiable in Children

MONDAY, June 22, 2020 (HealthDay News) — Metabolic traits associated with adult diabetes risk may be detectable by age 8 years, according to a study published online June 19 in Diabetes Care.

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Sugar-Sweetened Beverage Tax Will Generate Health Gains

MONDAY, June 22, 2020 (HealthDay News) — Sugar-sweetened beverage tax designs are expected to generate substantial health gains and cost savings, according to a study published online June 22 in Circulation.

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2019 Screening Guidelines Would Label More as T2DM Cases

FRIDAY, June 19, 2020 (HealthDay News) — Adopting the 2019 Endocrine Society guidelines for diabetes screening would substantially increase the number of older adults classified as having type 2 diabetes but would likely offer limited benefits, according to a study recently published in Diabetes Care.

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22 Percent Worldwide at Increased Risk for Severe COVID-19

FRIDAY, June 19, 2020 (HealthDay News) — About 22 percent of the global population has at least one underlying condition that places them at increased risk for severe COVID-19, according to a modeling study published online June 15 in The Lancet Global Health.

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Editorial

Court Rules Against Drug Price Disclosures in TV Ads

THURSDAY, June 18, 2020 (HealthDay News) — The U.S. government does not have the legal authority to force drug companies to disclose prices in their TV ads, a federal appeals court says.

AP News Article

Hyperglycemia Common in T1DM Patients With COVID-19

THURSDAY, June 18, 2020 (HealthDay News) — Presentation patterns are similar in patients with type 1 diabetes admitted with confirmed or suspected COVID-19, according to a study published online June 5 in Diabetes Care.

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Telehealth Counseling Cuts Weight Regain in Rural Communities

THURSDAY, June 18, 2020 (HealthDay News) — For individuals in rural communities, extended care for obesity management via individual telephone counseling reduces weight regain, according to a study published online June 15 in JAMA Network Open.

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Editorial

Continuous Glucose Monitoring Aids Glycemic Control in Young

WEDNESDAY, June 17, 2020 (HealthDay News) — Continuous glucose monitoring (CGM) improves glycemic control in adolescents and young adults with type 1 diabetes and is beneficial for hypoglycemia in older adults with type 1 diabetes, according to two studies published in the June 16 issue of the Journal of the American Medical Association.

Abstract/Full Text – Laffel (subscription or payment may be required)

Abstract/Full Text – Pratley (subscription or payment may be required)

Editorial (subscription or payment may be required)

Mild Thyroid Dysfunction Common in Women With Subfertility

WEDNESDAY, June 17, 2020 (HealthDay News) — Among women with a history of miscarriage or subfertility trying for a pregnancy, mild subclinical hypothyroidism (SCH) is common, according to a study published online June 17 in the Journal of Clinical Endocrinology & Metabolism.

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Stressful Life Events May Up CHD Risk in Type 2 Diabetes

TUESDAY, June 16, 2020 (HealthDay News) — Higher levels of stressful life events are associated with a higher risk for coronary heart disease (CHD) among postmenopausal women with type 2 diabetes, according to a study published online June 4 in Diabetes Care.

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Hip, Nonvertebral Fracture Risk Up in Those With Diabetes

MONDAY, June 15, 2020 (HealthDay News) — Individuals with diabetes have an increased risk for hip and nonvertebral fractures, according to a study published in the August issue of Bone.

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Stay-at-Home Orders Challenging Obese Patients

FRIDAY, June 11, 2020 (HealthDay News) — Obese patients are reporting physical and mental health challenges during the COVID-19 stay-at-home orders, according to a study published online June 9 in Clinical Obesity.

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Sleep Apnea in Patients With T2DM Ups Risk for Comorbidities

FRIDAY, June 12, 2020 (HealthDay News) — Patients with type 2 diabetes who develop obstructive sleep apnea (OSA) are at higher risk for cardiovascular disease (CVD) and other diabetes-related complications, according to a study recently published in Diabetes Care.

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Risk Factors for Suicide ID’d in Health Care Professionals

THURSDAY, June 11, 2020 (HealthDay News) — Modifiable and nonmodifiable risk factors for suicide have been identified among health care professionals, according to a study published online June 10 in JAMA Surgery.

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Editorial (subscription or payment may be required)

Joint Framework Issued to Spur Diabetes Education, Support

THURSDAY, June 11, 2020 (HealthDay News) — In a joint position statement from seven leading diabetes organizations, published online June 8 in Diabetes Care, a framework is presented to increase use of diabetes self-management education and support (DSMES) in patients with type 2 diabetes.

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Low-Dose Aspirin Lowers CVD Risk but Raises Bleeding Risk

WEDNESDAY, June 10, 2020 (HealthDay News) — Low-dose aspirin significantly lowers cardiovascular disease (CVD) risk but increases the risk for bleeding, according to a review published online June 2 in the British Journal of Clinical Pharmacology.

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Diet, Activity Guideline Updated by American Cancer Society

TUESDAY, June 9, 2020 (HealthDay News) — The diet and physical activity guideline for the prevention of cancer has been updated by the American Cancer Society; the guideline was published online June 9 in CA: A Cancer Journal for Clinicians.

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Pneumonia Risk Down With Nitrogen-Containing Bisphosphonates

FRIDAY, June 5, 2020 (HealthDay News) — For patients with hip fracture, receipt of nitrogen-containing bisphosphonates (N-BPs) is associated with a lower risk for pneumonia and pneumonia mortality, according to a study published online June 2 in the Journal of Bone and Mineral Research.

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Perfluoroalkyl Substances Linked to Earlier Natural Menopause

THURSDAY, June 4, 2020 (HealthDay News) — Perfluoroalkyl substances (PFAS) are associated with earlier natural menopause, according to a study published online June 3 in the Journal of Clinical Endocrinology & Metabolism.

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Workplace Wellness Programs Do Not Impact Clinical Outcomes

WEDNESDAY, June 3, 2020 (HealthDay News) — A comprehensive workplace wellness program may change employee health beliefs and increase self-reporting of having a primary care physician but does not significantly affect clinical outcomes, according to a study published online May 26 in JAMA Internal Medicine.

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Editorial (subscription or payment may be required)

Weight, Blood Pressure Higher in Younger Patients With T2DM

WEDNESDAY, June 3, 2020 (HealthDay News) — Younger people who are diagnosed with type 2 diabetes have higher weight and blood pressure (BP) than similarly aged people without diabetes, according to a study published online May 21 in Diabetologia.

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Out-of-Pocket Spending Averages $2,414 Per Year for T1DM Costs

TUESDAY, June 2, 2020 (HealthDay News) — For privately insured patients with type 1 diabetes, mean out-of-pocket spending is $2,414 per year, according to a research letter published online June 1 in JAMA Internal Medicine.

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Editorial (subscription or payment may be required)

BMI, Tracheal Intubation/Death Linked in Diabetes With COVID-19

TUESDAY, June 2, 2020 (HealthDay News) — Body mass index (BMI) is associated with tracheal intubation and/or death within seven days among individuals with diabetes hospitalized for COVID-19, according to a study published online May 29 in Diabetologia.

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Adherence to Diabetes Meds May Cut Mortality in Colorectal Cancer

TUESDAY, June 2, 2020 (HealthDay News) — For patients with colorectal cancer and diabetes, adherence to diabetes medication is associated with better survival, according to a study published online June 1 in Cancer, Epidemiology, Biomarkers & Prevention.

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Insulin Resistance May Add to Racial Disparity in Breast Cancer Prognosis

MONDAY, June 1, 2020 (HealthDay News) — Insulin resistance is one factor mediating part of the association between race and poor prognosis in breast cancer, according to a study published online May 12 in Breast Cancer Research.

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Thyroid Dysfunction in Pregnancy Overdiagnosed, Overtreated

MONDAY, June 1, 2020 (HealthDay News) — Current practice patterns relating to testing and management of thyroid-stimulating hormone (TSH) during pregnancy are associated with overdiagnosis and overtreatment of hypothyroidism, according to a study published online June 1 in CMAJ, the journal of the Canadian Medical Association.

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