In part 5 of this Exclusive Interview, Jon Odorico talks with Diabetes in Control during the ADA 2018 convention in Orlando about the work to resolve some of the challenges in stem cell-derived beta cell research.
Jon Odorico MD is Director of the Pancreas and Islet Cell Transplantation Programs and Professor in the Department of Surgery, Division of Organ Transplantation at the University of Wisconsin-Madison School of Medicine and Public Health.
Transcript of this video segment:
What are Researchers Doing to Tackle These Challenges in Stem Cell-Derived Beta Cell Research?
Odorico: With the challenges I mentioned, academic and also industry scientists are approaching each of these individual aspects, including immunogenicity, tumorgenicity, transplant sites and improved functionality and a variety of research is going on in those areas. For example, people are looking at what causes cell death after transplantation and people are understanding that there are nutritional deficits and hypoxia is playing a role as well as cytokines in those areas.