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Early Insulin May Help
Diabetics Avoid It Later
A short course of insulin therapy
may help people newly diagnosed with
type 2 diabetes avoid this therapy later.
Reducing blood glucose quickly pays
off in long run.
In type 2 diabetes, insulin production
continues (unlike the situation in type
1 diabetes) but the body's response
to the hormone is blunted. Standard
drug treatment is aimed at increasing
sensitivity to insulin, but in some
cases extra insulin becomes necessary
on an ongoing basis to ensure that glucose
is processed properly.
The new findings, which appear in the
medical journal Diabetes Care, are based
on a study of 16 patients with newly
diagnosed type 2 diabetes who were treated
with intensive insulin therapy for 2
to 3 weeks. All of the subjects had
high blood sugar levels when the study
began.
This short-term therapy produced a marked
improvement in sugar levels, lead author
Dr. Edmond A. Ryan and colleagues, from
the University of Alberta in Edmonton,
note. Moreover, this improvement was
still present one year later.
At 1-year follow-up, only one patient
required insulin, while the rest were
able to control their sugar levels with
diet or pills. Predictors of good control
with diet alone included requiring less
insulin during the initial treatment
phase, and having a lower sugar level
at the end of that phase.
"The ease with which (normal sugar
levels are) achieved on insulin may
predict those patients who can later
succeed in controlling glucose levels
with attention to diet," the researchers
conclude. "However, the numbers
in this study were small, and the results
need confirmation with larger studies
before being considered as a routine
clinical option." Diabetes Care,
May 2004.
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FACT:
A new study shows us that if you
provide free test strips, people
will test more often.
Researchers from the Department
of Internal Medicine at the University
of Manitoba in
Canada studied 2 randomized groups,
one paid for strips and one group
was given free strips. The group
that had free strips tested 2x
daily and the other group tested
1.4X daily. The group that had
to pay for the strips had their
A1c’s go up, while the group
that got free strips kept their
A1c’s stable.
Diabetic Medicine Feb. 2004 |
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