Study Finds Way To Burn Fat
Without Exercise – The Magic Pill
Japanese researchers claim to have found a
way to get rid of excess fat without exercising,
in a breakthrough which could lead to better
treatment for obesity and diabetes.
When a cellular receptor in muscles known as
peroxisome proliferator-activated receptor
delta, or PPARd, is chemically activated, it
induces fat consumption in the muscle according
to research led by Tokyo University professor of
metabolic medicine Juro Sakai.
Receptors are proteins that translate a
certain type of stimulus into nerve impulses.
Calling PPARd "a fat-burning
sensor," professor Sakai, who leads a
research group at the elite university's
Research Centre for Advanced Science and
Technology, said the finding offers "the
possibility" of a drug that could end
obesity.
The drug could also be a treatment for
diabetes as the PPARd activation also increased
obese laboratory mice' sensitivity to insulin
and help reduce their blood sugar levels, he
told AFP.
"I believe the development will come in
the not-so-distant future although we have to
clear high hurdles for application in
humans," Sakai said.
"Even if you do not exercise, metabolic
activity accelerates, leading to weight
loss," Professor Sakai said.
"Of course I do not intend to dismiss
the notion of taking exercise as it is still the
best way," to get rid of fat, he added.
The study found weight gain among mice given
high-fat feed whose PPARd receptors had been
activated was about 40 per cent less than
untreated mice on the same diet.
The activation of PPARd caused no excess
weight loss as it worked less dramatically on
non-obese mice, Professor Sakai said. He also
said it does not trigger excessive eating.
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