Treating Pre-Diabetes with Increased
Fiber Consumption To Prevent Diabetes
High intake of dietary fiber is associated
with enhanced insulin sensitivity.
The purpose of the study was to examine cross-sectional
associations of dietary fiber intake with insulin
resistance, insulin secretion, and glucose tolerance
in a population at high risk for type 2 diabetes.
The subjects consisted of 248 male and 304 female
adult nondiabetic relatives of patients with type
2 diabetes. Dietary intake was measured by means
of two 3-day food records. Associations of total,
water-insoluble, and water-soluble fiber with
measures of glucose metabolism based on an oral
glucose tolerance test, were analyzed by multiple
linear regression analysis adjusting for sex,
age, length of education, physical activity, BMI,
waist-to-hip ratio, systolic blood pressure, and
serum triglyceride and HDL cholesterol concentrations.
The homeostasis model assessment insulin resistance
index, the incremental 30-min serum insulin concentration
divided by the incremental 30-min glucose concentration,
and fasting and 2-h glucose concentrations were
the outcome variables.
The results showed that the dietary intake of
total as well as water-insoluble and water-soluble
fiber was inversely associated with insulin resistance:
-0.17 (0.07), P = 0.012; -0.15 (0.07), P = 0.024;
and -0.14 (0.07), P = 0.049 [regression coefficients
(SE)]. Fiber variables were unrelated to insulin
secretion and plasma glucose concentrations.
In conclusion, the results support evidence that
a high intake of dietary fiber is associated with
enhanced insulin sensitivity and therefore may
have a role in the prevention of type 2 diabetes.
Associations of Dietary Fiber With Glucose Metabolism
in Nondiabetic Relatives of Subjects With Type
2 Diabetes
The Botnia Dietary Study : Diabetes Care 26:1979-1985,
2003
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Did YOU KNOW:
Medicare spends %13,243 on each recipient with
diabetes, compared to $2,560 for people without
diabetes. It represents 27% of the Medicare Budget.
The JDRF rep[orts that one in four Medicare dollars
is spent on diabetes. On top of this, the expenses
a person with diabetes faces are 2.4 times higher
than medical expenses for people without diabetes.
Diabetes Care March 2003
