ADA: Vardenafil (Levitra) Provides
Sexual Benefits in Diabetic Men
Vardenafil improves the key variables that determine
sexual satisfaction in men with coexisting diabetes
and erectile dysfunction (ED).
Irwin Goldstein, MD, from Boston University,
in Boston, Massachusetts, presented results at
the 63rd Scientific Sessions of the American Diabetes
Association.
452 men with type 1 or 2 diabetes and ED for
at least 6 months who were randomized to 12 weeks
of treatment with placebo, vardenafil 10 mg, or
vardenafil 20 mg.
Individuals who had sustained a significant cardiovascular
event in the 6 months prior to the study or who
had active proliferative retinopathy or retinitis
pigmentosa were excluded from the trial
The mean per-patient success rate for vaginal
penetration and for sexual intercourse was 64%
and 54%, respectively, for the 20 mg dose. Overall,
72% of patients who completed the study and were
treated with the 20 mg dose reported improved
erections.
Vardenafil 20 mg significantly improved the level
of satisfaction with erection hardness, satisfaction
with the sexual experience, ability to ejaculate,
domains of intercourse satisfaction and orgasmic
function on the International Index of Erectile
Dysfunction (IIEF).
Adverse events were those that typically occur
with PDE5 inhibitors, and included headache, flushing,
rhinitis and sinusitis.
"In this challenging population of men with
ED and diabetes, vardenafil improved key aspects
of the sexual experience important to quality
of life," Dr. Goldstein said. "In fact,
rates of satisfaction and erection hardness were
three times greater with the 20 mg dose of vardenafil
compared to placebo."
Overall, about 50% of men develop erectile dysfunction
within 10 years of being diagnosed with diabetes,
he added. This study was carried out at 47 sites
in the US and Canada.
[Study title: Vardenafil (Levitra) Improved Satisfaction
with Erectile Hardness, Orgasmic Function and
Sexual Experience in Men with Diabetes with Erectile
Dysfunction. Abstract 68]
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Did YOU KNOW: In 1995, 62% ofpeople
with diabetes in the world lived in developing
countries. By 2025 this is predicted to rise to
more than 75% (IDF Diabetes Voice May 2003).
