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Item #11
Noninvasive
Blood Glucose Monitor Getting Closer to Introduction
This
noninvasive blood glucose monitor measures concentrations of serum
glucose with clinically acceptable accuracy and avoids individual
daily calibration.
A
group of investigators led by Dr Carl Malchoff of the University of
Connecticut Health Center in the USA, evaluated an advanced prototype
of a blood glucose monitor. The monitor is a handheld, noninvasive
device that uses principles of thermal emission spectroscopy. The
researchers calibrated the prototype using 432 paired measurements of
concentrations of serum glucose from 20 patients with diabetes who
required insulin. The monitor was then evaluated blindly in 126 paired
measurements from six patients with diabetes who required insulin.
Measurements were also compared with laboratory reference values using
an error-in-variables method.
The
investigators showed that the measurements taken with the blood
glucose monitor were reproducible. For the six patients studied, the
standard deviation in measurements was 32mg/dL, the percent mean
absolute relative error (%MARE) was 11.6 and the correlation
coefficient was 0.87. For all measurements, the standard deviation was
27mg/dL, the %MARE was 8.6 and the correlation coefficient was 0.94. A
Clark Error Grid analysis showed that all the measurements fell within
zones A and B, with 90% falling within zone A. The investigators
conclude that this noninvasive blood glucose monitor measures
concentrations of serum glucose with clinically acceptable accuracy
and avoids individual daily calibration. Diabetes Care
2002;25:2268-75
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DID
YOU KNOW: The
2003 update of the American Heart Association's Heart Disease and
Stroke Statistics examined the correlation between physical activity
and heart disease. People who are inactive are 1.5 to 2.4 times more
likely to develop heart disease.
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out the Open Fiber Study (Click
Here)
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