Fasting
Glucose Inadequate in Screening for CV Risk
Two-thirds
of subjects with cardiovascular risk factors remain undetected using
fasting glucose testing as a screening method, say researchers.
Fasting
glucose inadequate in screening for CV risk
The
researchers used a two-step strategy to compare metabolic risk
profiles in subjects with impaired glucose fasting (IFG) and those
with impaired glucose tolerance (IGT). They identified 1,855 people
without diagnosed diabetes with fasting plasma glucose of between
5.6-7.8 mmol/l. Those patients were asked to complete an oral glucose
tolerance test (OGTT; n=1,456).
The
results between the two measurements only agreed in 20.8% of the
subjects. Those with isolated IFG did not have clinical features
associated with cardiovascular risk, whereas subjects with IGT had
associated cardiovascular risk profiles. The researchers commented
that if IFG were used for glucose intolerance screening about 66.6% of
subjects with IGT with cardiovascular risk would not have been
detected.
Li
CL et al. Comparison of metabolic risk profiles between subjects with
fasting and 2-hour plasma glucose impairment: The Kinmen Study. J Clin
Epidemiol 2002; 55: 19-24.
Did
you know?
According
to recent survey by IDF and Lyons, The majority of people with
diabetes are not worried about long-term complications of the disease,
even though 74 percent of people with diabetes may suffer diabetic
microvascular complications.
