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Item #15 

Vascular Surgery Safer than Amputation for Diabetics

New study shows a lower morbidity rate after vascular surgery and is even lower than those who don’t have the disease.

Diabetics are often advised to avoid vascular surgery because the operation could make them worse instead of better; they're even told they're better off having a leg amputated than having the procedure.

However, a new study should put diabetics at ease. It finds that, in the short run, their risk of dying after vascular surgery was actually lower than that of those who didn't have the disease.

Doctors at Boston's Beth Israel Deaconess Medical Center reviewed surgical outcomes of 6,565 patients over a 10-year period, and found diabetics had just under a 1 percent mortality rate following major vascular surgery. In previous studies, the death rate on the procedure has been as high as 4 percent, says study author Dr. Allen D. Hamdan.

"Having diabetes does not predict a higher risk for vascular surgery. In fact, there was a lower morbidity rate," says Hamdan, a vascular surgeon at Deaconess and an assistant professor of surgery at Harvard Medical School. "What this means is that people with diabetes should be treated like anyone else, on a case-by-case basis, with regard to surgery."

There are about 16 million diabetics in the United States, and 800,000 new cases are diagnosed each year, Hamdan says. The disease compromises the circulatory system, so diabetics have significantly more vascular problems such as clotting and risk of gangrene in their outer limbs.

"It is an underlying truth" that patients with diabetes have accelerated hardening of the arteries that leads to problems all over the body at an earlier age and at a more accelerated rate, he says.

This led to the belief that "diabetics were felt to have a different type of vascular damage than non-diabetics. The feeling was that those with diabetes had worse blockages than people without diabetes," Hamdan says. "Because of this, simply the presence of diabetes was thought to be an indicator of higher risk for surgery."

As a result, he says, patients were -- and still are -- often advised to have amputations rather than vascular surgery that might improve circulation.

However, Hamden and his colleagues statistically analyzed outcomes for surgeries in the arteries of the neck and extremities, as well as arteries leading to the heart. They found diabetics had a death rate of 0.96 percent, compared with a 1.46 percent rate for non-diabetics who had the same operation. Hamden says the results were a surprise.

"Diabetics are at much more higher risk for vascular problems, so the results are very surprising," says Renee Meehan, the diabetic clinical nurse specialist at Tampa General Hospital in Florida.

The study also found, however, that diabetics were at a slightly higher risk of having a heart attack after the procedure. Moreover, the long-term survival rate was "significantly lower" among diabetics than in the non-diabetics.

SOURCES: Allen D. Hamdan, M.D., vascular surgeon, Beth Israel Deaconess Medical Center, and assistant professor, surgery, Harvard Medical School, Boston; Renee Meehan, R.N., B.S.N., M.A., C.D.E., diabetic clinical nurse specialist, Tampa General Hospital, Tampa, Fla.; April 2002 Archives of surgery~DIAB~~HRTS~~SURG~


Fact:

For every one-percentage point drop in the Hemoglobin A1c diabetes complication rates drop by more than 25%.    Source: Diabetes 2001: Vital Stats.

 

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