|
Item
#5
Aggressive
Blood Pressure Control in Diabetes Prevents Complications
Study
showed, less progression of diabetic retinopathy and
microalbuminuria.
A
group of researchers led by Dr Schrier from the University of
Colorado Health Sciences, USA, studied the effect of intensive
versus moderate BP control on diabetic vascular complications in
normotensive type 2 diabetes patients. Overall, 480 patients were
randomized to intensive (target 10mmHg below the baseline
diastolic BP) or moderate (target 80 to 89mmHg) diastolic BP
control. Patients in the intensive group received nisoldipine or
enalapril, and those in the moderate group received placebo.
The
researchers showed that after a mean follow-up of 5.3 years, mean
BP was significantly lower in the intensive group (128±0.8/75±0.3mmHg)
compared with the moderate group (137±0.7/81±0.3mmHg;
p<0.0001). A lower percentage of patients in the intensive
group progressed from normoalbuminuria to microalbuminuria
compared with those in the moderate group (p=0.012). There was
also less progression of diabetic retinopathy (p=0.019), and a
lower incidence of strokes (p=0.03) in the intensive group
compared with the moderate group.
There
were no significant differences in the results between nisoldipine
and enalapril.
Kidney
International 2002;61:1086-97
================================
DID
YOU KNOW?
The
number of Americans with diabetes jumped 50 percent from 1990 to
2000
By
referring your friends and colleagues to Diabetes in Control you
can win a free scholarship or expense check for the 2002 AADE
conference in Philadelphia.
http://www.diabetesincontrol.com/scholorship.shtml
Back / Next Item
[an error occurred while processing this directive]
|
