Insulin prices far outweigh product costs. The cost to make a vial of human insulin is $2.28 to $3.42, and a vial of most analog insulins costs $3.69 to $6.16 to produce. In a current study in BMJ Global Health, after analyzing expenses for ingredients, production, and delivery, among other things, the researchers contend that the price for a year’s supply of human insulin could be $48 to $71 per person and between $78 and $133 for analog insulins, which are genetically altered forms that are known as rapid- or long-acting treatments. Examples of analog insulins include Humalog, Lantus, and Novolog. The question comes up, how can pharmaceutical companies justify charging on average more than a thousand dollars a year? Just as the cost for blood glucose strips have come down significantly after the process was opened up to a bidding process, or maybe prevent rebates to managed care organizations and PBM’s for putting certain brands on their formularies. As medical professionals, we need to participate in getting the cost down for insulin which is required to live. — JAMA. 2016;315(13):1400-1402. doi:10.1001/jama.2016.0126 BMJ Global Health.