Yearly screening for depression in patients with type 2 diabetes can decrease negative health outcomes and can be a cost-effective way to reduce complications, according to current research. After a literature review of studies examining the relationship between depression and glycemic control, they respectively, aimed to develop a protocol for consistent depression screening for adult patients with type 2 diabetes; secondary outcomes included evaluation of clinic staff perceptions surrounding depression screening in diabetes.  Of the 10 studies reviewed, 7 showed a “statistically significant” association between depression and inadequate glycemic control and 3 found that recognition of depressive symptoms, in conjunction with appropriate follow-up and treatment, led to improved A1c levels. The proposed protocol would collect baseline data, including age, sex, comorbidities, and history of depression. Patients would complete the Patient Health Questionnaire-2; patients scoring positive for depression would complete the Patient Health Questionnaire-9. After electronic documentation, clinicians should review HbA1c levels and offer either referral or treatment for depression. By following this protocol, patients with type 2 diabetes may experience fewer, and less expensive, complications, as well as lower A1c levels over time.  “Patients with major depressive disorder have a mean life span of 25 to 30 years less than the average person,” the researchers noted.  The purpose of this project was not only to identify and treat patients with diabetes, but also implement a sustainable process to screen these patients…for depression.–Presented at the American Association of Nurse Practitioners (AANP) 2017 National Conference, held June 20 to 25 in Philadelphia, Pennsylvania.