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The reason for this is unclear, but screening for and aggressively treating diabetes may improve the outcomes of patients receiving tuberculosis therapy, Dr. Reinout van Crevel, from Radboud University Medical Center in Nijmegen, note in the current issue Clinical Infectious Diseases.
The findings stem from a study of 737 Indonesian patients with tuberculosis who were screened for type 2 diabetes, also referred to as adult-onset diabetes, and then followed while receiving tuberculosis therapy.
Overall, 14.8 percent of the subjects had diabetes. Despite initially having more symptoms, the patients with diabetes had tuberculosis that was comparable in severity to that in non-diabetics.
However, after 2 months of treatment, sputum test results were more likely to be positive in diabetic patients --18.1 percent vs. 10.0 percent in non-diabetics. At 6 months, the diabetes were still significantly more likely to have positive sputum test results than the non-diabetic patients, at 22.2 percent vs. 9.5 percent, respectively.
In a related editorial, Dr. Blanca I. Restrepo, from the University of Texas Health Science Center in Houston, comments that the findings "highlight the need for further research aimed at understanding how the current global epidemic of type 2 diabetes mellitus is affecting tuberculosis control and prevention."
Clinical Infectious Diseases, August 15, 2007.
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DID YOU KNOW: Whole Grains Protect Against Diabetes: Whole grains may help prevent type 2 diabetes, with consistent results across studies, researchers said. The risk of developing type 2 diabetes dropped 21% with every two additional servings of whole grain per day. Their analysis of two Nurses' Health Study cohorts and four other cohort studies showed a significant benefit to whole grain, particularly its bran component, in five of the studies. "The consumption of whole grains in many populations is very low, an average of one serving per day for U.S. adults and even less in British adults, suggesting that increased consumption has the potential to contribute substantially to reducing risk of type 2 diabetes in these populations," Dr. van Dam and colleagues wrote. See this weeks Item#12
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