If successful, researchers believe it could offer thousands of children protection from the disease, and the opportunity to avoid a life of constant blood-sugar monitoring, insulin injections and a regimented diet.

Researchers from the University of Melbourne's Diabetes Vaccine Development Centre are seeking 13,000 people aged between four and 30 who have a blood relative with Type 1 diabetes - and a higher risk of developing the disease - to undergo screening for the trial.

As part of the four-year program, young people will self-administer the intranasal spray every day for one week, and then once a week for a year, while receiving regular health checks to determine if the onset of diabetes has been delayed or prevented.
A spokeswoman for the National Health and Medical Research Council (NHMRC) said the nasal spray encouraged the body's protective immune cells to fight the onset of the disease.

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