Main Newsletter
Mastery Series
Therapy Series
 
Bookmark and Share | Print Article | Items for the Week Previous | All Articles This Week | Next
This article originally posted and appeared in  ObesityType 2 DiabetesGastroenterologySurgeryIssue 675

No Link between Diabetes Remission, Weight Regain after Gastric Bypass

Weight regain among diabetic patients who have undergone gastric bypass is not associated with remission of diabetes....

Advertisement

Researchers evaluated 652 patients who underwent laparoscopic Roux-en-Y gastric bypass (LRYGBP) at a single facility between March 2003 and December 2009. Follow-up was performed for a mean of 2.88 years after surgery. The cohort included 170 patients who had preoperative type 2 diabetes mellitus (T2DM).

Across all participants, the mean maximum excess weight loss (EWL) was 77.1%, with two-thirds of participants regaining an average of 19.1% of maximum EWL during follow-up. Most patients with T2DM (82.7%) were in remission upon completion of follow-up, with 5.8% of those with diabetes experiencing recurrence after remission. Recurrence was significantly associated with insulin use (75% compared with 18%) and longer T2DM duration (12.3 years vs. 6 years) compared with those who did not experience recurrence. Investigators said neither the maximum EWL nor the amount of weight regained were significantly different between recurrent and nonrecurrent patients.

"Weight regain after LRYGBP is common, but not associated with remission," the researchers concluded. "Recurrence of T2DM after remission … is associated with longer duration of T2DM and insulin use. Early surgical intervention for morbidly obese patients with T2DM should be recommended to maximize remission rates."

Presented at the Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting in Baltimore. April 17, 2013, Taitano AA. P005: Weight Regain Does Not Impact Remission of Diabetes After Gastric Bypass.  

Advertisement


 

Bookmark and Share | Print | Category | Home

This article originally posted 03 May, 2013 and appeared in  ObesityType 2 DiabetesGastroenterologySurgeryIssue 675

Past five issues: Diabetes Clinical Mastery Series Issue 208 | Issue 748 | GLP-1 Special Editions September 2014 | Diabetes Clinical Mastery Series Issue 207 | Issue 747 |

2014 Most Popular Articles:

Abbott Announces Approval of Its New Unique Continuous Glucose Monitor
Posted September 05, 2014
Low Carb Beats Low Fat
Posted September 05, 2014
FDA Approves Bupropion/Naltrexone (Contrave) for Obesity by Orexigen Therapeutics
Posted September 12, 2014
Lilly's Basal Insulin Peglispro Demonstrated HbA1c Superiority against Lantus
Posted September 05, 2014
An Exclusive Interview with Al Mann, Founder and CEO, Mannkind Corp.
Posted September 15, 2014
Sleeve Gastrectomy Now a Common Choice for Bariatric Surgery
Posted September 12, 2014
Type 2 Diabetes Diagnosis Needs to Be Changed: Prediabetes=Diabetes
Posted September 12, 2014
FDA Approves Once-Weekly GLP-1 Diabetes Treatment Regimen for T2DM
Posted September 25, 2014
Predicting Which Diabetics Will Develop Major Complications
Posted September 05, 2014
High-salt Diet and High HBA1c May Increase Cardiovascular Disease
Posted September 19, 2014


Browse by Feature Writer & Article Category.
A. Lee Dellon, MD | Aaron I. Vinik, MD, PhD, FCP, MACP | Beverly Price | Charles W Martin, DD | Derek Lowe, PhD | Dr. Bernstein | Dr. Brian Jakes, Jr. | Dr. Fred Pescatore | Dr. Tom Burke, Ph.D | Eric S. Freedland | Evan D. Rosen | Ginger Kanzer-Lewis | Greg Milliger | Kristina Sandstedt | Laura Plunkett | Leonard Lipson, M.A. | Louis H. Philipson | Maria Emanuel Ryan, DDS, PhD | Marilyn Porter, RD, CDE | Melissa Diane Smith | Michael R. Cohen, RPh, MS, ScD, FASHP | Paul Chous, M.A., OD | Philip A. Wood PhD | R. Keith Campbell, Professor, B.Pharm, MBA, CDE | Sheri R. Colberg PhD | Sherri Shafer | Stanley Schwartz, MD, FACP, FACE | Steve Pohlit | Steven V. Edelman, M.D. | Timothy S. Hollingshead |

Cast Your Vote
Now that once-weekly dulaglutide has been approved, will you be prescribing it?
CME/CE of the Week
Ronald Tamler, MD, PhD, MBA

Category: General Diabetes
Credits: .75
Search Articles On Diabetes In Control