Main Newsletter
Mastery Series
Therapy Series
 
Bookmark and Share | Print Article | Items for the Week Previous | All Articles This Week | Next
This article originally posted and appeared in  ObesityType 2 DiabetesGastroenterologySurgeryIssue 675

No Link between Diabetes Remission, Weight Regain after Gastric Bypass

Weight regain among diabetic patients who have undergone gastric bypass is not associated with remission of diabetes....

Advertisement

Researchers evaluated 652 patients who underwent laparoscopic Roux-en-Y gastric bypass (LRYGBP) at a single facility between March 2003 and December 2009. Follow-up was performed for a mean of 2.88 years after surgery. The cohort included 170 patients who had preoperative type 2 diabetes mellitus (T2DM).

Across all participants, the mean maximum excess weight loss (EWL) was 77.1%, with two-thirds of participants regaining an average of 19.1% of maximum EWL during follow-up. Most patients with T2DM (82.7%) were in remission upon completion of follow-up, with 5.8% of those with diabetes experiencing recurrence after remission. Recurrence was significantly associated with insulin use (75% compared with 18%) and longer T2DM duration (12.3 years vs. 6 years) compared with those who did not experience recurrence. Investigators said neither the maximum EWL nor the amount of weight regained were significantly different between recurrent and nonrecurrent patients.

"Weight regain after LRYGBP is common, but not associated with remission," the researchers concluded. "Recurrence of T2DM after remission … is associated with longer duration of T2DM and insulin use. Early surgical intervention for morbidly obese patients with T2DM should be recommended to maximize remission rates."

Presented at the Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting in Baltimore. April 17, 2013, Taitano AA. P005: Weight Regain Does Not Impact Remission of Diabetes After Gastric Bypass.  

Advertisement


 

Bookmark and Share | Print | Category | Home

This article originally posted 03 May, 2013 and appeared in  ObesityType 2 DiabetesGastroenterologySurgeryIssue 675

Past five issues: Issue 760 | Diabetes Clinical Mastery Series Issue 219 | SGLT-2 Inhibitors Special Edition December 2014 | Issue 759 | Diabetes Clinical Mastery Series Issue 218 |

2014 Most Popular Articles:

New Guidelines for Doctors to Treat Diabetes
Posted December 12, 2014
Handbook of Diabetes, 4th Ed., Excerpt #20: Foot Problems in Diabetes
Posted November 29, 2014
Why Are Up to 20% Type 2's Nonresponsive to Exercise?
Posted December 05, 2014
Is Type 2 Diabetes an Inflammatory Disease?
Posted November 21, 2014
Carbs Associated with Higher Diabetes and Heart Disease Risk Factor
Posted December 05, 2014
Handbook of Diabetes, 4th Ed., Excerpt #19: Macrovascular Disease in Diabetes
Posted November 23, 2014
Any Pain Medication Said Effective When Treating Diabetic Nerve Pain
Posted November 21, 2014
Knowledge of Onset, Peak, and Duration of Action of Meds Prevents a Trip to the ER
Posted November 24, 2014
Link between Free Fatty Acids and Acute MI, Type 2 Diabetes
Posted November 21, 2014
New Approach Targets Type 2's Poorly Controlled With Metformin
Posted November 14, 2014


Browse by Feature Writer & Article Category.
A. Lee Dellon, MD | Aaron I. Vinik, MD, PhD, FCP, MACP | Beverly Price | Charles W Martin, DD | Derek Lowe, PhD | Dr. Brian Jakes, Jr. | Dr. Fred Pescatore | Dr. Tom Burke, Ph.D | Eric S. Freedland | Evan D. Rosen | Ginger Kanzer-Lewis | Greg Milliger | Kristina Sandstedt | Laura Plunkett | Leonard Lipson, M.A. | Louis H. Philipson | Maria Emanuel Ryan, DDS, PhD | Marilyn Porter, RD, CDE | Melissa Diane Smith | Michael R. Cohen, RPh, MS, ScD, FASHP | Paul Chous, M.A., OD | Philip A. Wood PhD | R. Keith Campbell, Professor, B.Pharm, MBA, CDE | Richard K. Bernstein, MD | Sheri R. Colberg PhD | Sherri Shafer | Stanley Schwartz, MD, FACP, FACE | Steve Pohlit | Steven V. Edelman, M.D. | Timothy S. Hollingshead |

Cast Your Vote
For your prediabetes patients who can't lower their blood glucose with lifestyle changes, do you prescribe GLP-1s or SGLT-2s?
CME/CE of the Week
Ronald Tamler, MD, PhD, MBA

Category: General Diabetes
Credits: .75
Search Articles On Diabetes In Control