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This article originally posted and appeared in  DietObesityPreventionIssue 589

Weight Loss through Cutting Calories Results Less than Expected

Common rules of thumb exaggerate how much weight people will lose from a given dietary calorie reduction, leading to unrealistic expectations and disappointment, researchers said....


According to Kevin D. Hall, PhD, of the National Institute of Diabetes and Digestive and Kidney Diseases in Bethesda, Md, whereas patients are often told that cutting 500 calories a day will let them lose a pound a week, a more realistic formula is that such a caloric reduction would lead to a 50-pound loss over three or more years.

Even then, such weight loss is possible only if the calorie reduction is actually maintained over that time. The standard rules -- endorsed by the National Institutes of Health and the American Dietetic Association, among others -- fail to consider that human metabolism responds dynamically to changes in diet and body composition, Hall and colleagues asserted.

If a 300-pound dieter could really lose a pound a week by cutting his regular diet by 500 calories, he would vanish entirely in six years.

"This ubiquitous weight-loss rule (also known as the 3,500 [calorie]-per-pound rule) was derived by estimation of the energy content of weight lost, but it ignores dynamic physiological adaptations to altered body weight that lead to changes of both the resting metabolic rate as well as the energy cost of physical activity," the researchers wrote.

When people gain weight, their baseline energy needs increase, to keep the extra tissue alive and to move it around. Likewise, when weight is lost, their baseline needs decrease.

So when people cut calories below the baseline requirement -- thereby triggering weight loss -- the gap between their intake and their baseline energy needs begins to shrink. At some point, it may disappear altogether, at which point weight loss stops.

Hall and colleagues put together what they said was a better model of caloric intake and resultant weight loss, incorporating feedback mechanisms to reflect metabolic changes over time in response to diet and body weight. It indicated that weight change in response to caloric restriction occurs over a relatively long period of time.

Each reduction of 100 kilojoules daily -- 24 calories -- in intake eventually leads to a loss of 1 kg (2.2 lbs) in body weight, the researchers determined. But only half that loss occurs in the first year. In three years, 95% of the ultimate loss will be realized.

On the flip side, using data from previous studies, Hall and colleagues said their calculations suggest that the U.S. population has a persistent excess energy intake of 30 kilojoules (7.2 calories) per day, explaining the increasing prevalence of overweight and obesity.

For the population to return to body mass index values that prevailed in the 1970s, average diets would need to shrink by about 220 calories per day.

The researchers pointed out that these figures are averages for the adult population. Individuals' metabolic requirements for sustaining a given body mass vary substantially. Consequently, "a given diet results in an uncertain degree of energy deficit," Hall and colleagues wrote.

The findings have important implications for policy, the researchers argued.

For example, they pointed to a 2010 policy paper from the U.S. Department of Agriculture, which included an estimate that a 20% tax on sugar-sweetened drinks would reduce average energy intake by 40 calories. Using the standard 3,500 calorie-per-pound rule, the paper indicated that an average weight loss of about 1.8 kg (4 lbs.) per year could be expected -- "incorrectly," Hall and colleagues contended. Their model shows that it would actually take five years to achieve that level of average weight loss.

"We suggest that unrealistic weight loss expectations obtained by erroneous use of the static dieting rule should be replaced by our methods to assess other population-wide and more targeted obesity prevention interventions," the researchers wrote.

They also pointed out that, in evaluating interventions, the model can also take account of physical activity and its effects on body weight and metabolism.

On the other hand, a limitation is that "it assumes perfect adherence to the intervention" and also doesn't automatically include increases in food intake that may accompany the start of an exercise program.

The problem, of course, is that adherence is usually anything but perfect. Moreover, it can be compounded by the long lag between changes in diet and changes in body weight.

One manifestation is that patients lose weight while on a program and continue to do so -- for a time -- after they revert to their former lifestyle. "The dieter might then incorrectly infer that adherence is not essential for continuing weight loss when, in fact, impending weight regain has already been set in motion," the researchers indicated.

Practice Pearls:
  • Explain that a study using mathematical modeling explains that weight loss and energy intake reduction are not static processes and require much more time than previously appreciated.
  • Point out that the formula predicts only 50% of weight loss within the first year and 95% by three years with a consistent calorie reduction.

Hall K, et al "Quantification of the effect of energy imbalance on bodyweight" Lancet 2011; 378: 826-37.



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This article originally posted 01 September, 2011 and appeared in  DietObesityPreventionIssue 589

Past five issues: Diabetes Clinical Mastery Series Issue 256 | Issue 796 | Diabetes Clinical Mastery Series Issue 255 | Issue 795 | SGLT-2 Inhibitors Special Edition August 2015 |

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