Sign up for our complimentary
weekly e-journal

Main Newsletter
Mastery Series
Therapy Series
 
Bookmark and Share | Print Article | Items for the Week Previous | All Articles This Week | Next
This article originally posted 08 February, 2012 and appeared in  Women's HealthType 2 DiabetesType 1 DiabetesChildren & TeensIssue 612

Women with Diabetes Are Four Times More Likely to Have a Baby with Birth Defects

Pregnant women with diabetes are almost four times more likely to have a baby with a birth defect than women without the condition, and the likelihood is linked to the mother's glucose level....

Advertisement

The study, led by researchers at Newcastle University and the Regional Maternity Survey Office, suggests that as many as 1-in-13 deliveries to women with Type 1 or Type 2 diabetes involves a major congenital anomaly, also known as a birth defect.

The analysis showed that the risk of a birth defect in the pregnancies of women with Type 1 or Type 2 diabetes was 7%, compared to an average of around 2% in pregnancies in which the mother did not have diabetes. The chance of a birth defect was reduced significantly in women with diabetes who had blood-glucose levels within the recommended ranges -- which, according to Diabetes UK, has highlighted the importance of healthcare teams encouraging women who are thinking of becoming pregnant to get their blood-glucose level as low as is safely possible.

But the researchers and Diabetes UK have emphasized that, while concerning, this still means that the vast majority of pregnancies in women with diabetes do not involve a birth defect. The study also showed that blood-glucose levels around the time of conception were the most important factor predicting risk of congenital anomaly.

The findings have prompted Diabetes UK to urge women with diabetes who are considering becoming pregnant to make sure they understand the importance of careful planning. 

"The risk of problems can be reduced by taking extra care to have optimum glucose control before becoming pregnant," stated Ruth Bell, the study's lead researcher. "Any reduction in high glucose levels is likely to improve the chances of a healthy baby." Previous research has established that having diabetes increases the chance of birth defects, but this is one of the first studies to quantify the effect of glucose levels on risk.

The study involved an investigation of the recorded outcomes of 401,149 pregnancies, including 1,677 pregnancies in women with diabetes, between 1996 and 2008 in the north of England.

Click here to see a "Video on Diabetes and Pre-conception"

Diabetologia, Feb. 2012
Advertisement


 

Bookmark and Share | Print | Category | Home

This article originally posted 08 February, 2012 and appeared in  Women's HealthType 2 DiabetesType 1 DiabetesChildren & TeensIssue 612

Past five issues: SGLT-2 Inhibitors Special Edition April 2014 | Diabetes Clinical Mastery Series Issue 184 | Issue 724 | Diabetes Clinical Mastery Series Issue 183 | Issue 723 |

2014 Most Popular Articles:

Patient Handout: 7 Tips to Drop Excess Pounds with Diabetes
Posted April 04, 2014
Who Qualifies for Statin Treatment under the New Guidelines?
Posted March 27, 2014
Updated Bolus Calculators for Diabetes Management
Posted March 20, 2014
Vitamin D's Effect on the Progression of Pre-type 1 Diabetes
Posted March 14, 2014
Surprising Trends in the Use of Antidiabetic Drugs
Posted March 27, 2014
A1C Is a Predictor of Clinical Outcomes Following Noncardiac Surgery
Posted March 14, 2014
Agavins: A Potential Alternative to Artificial Sweeteners
Posted March 27, 2014
Abdominal Fat Accumulation Prevented by Unsaturated Fat
Posted March 14, 2014
Evidence Shows Possible Benefit of Metformin and Glyburide Use in Pregnancy
Posted March 14, 2014
GLP-1 Agonist Interaction with Insulin-Induced Hypoglycemia
Posted March 27, 2014

See more most popular…


Browse by Feature Writer & Article Category.
A. Lee Dellon, MD | Aaron I. Vinik, MD, PhD, FCP, MACP | Beverly Price | Charles W Martin, DD | Derek Lowe, PhD | Dr. Bernstein | Dr. Brian Jakes, Jr. | Dr. Fred Pescatore | Dr. Tom Burke, Ph.D | Eric S. Freedland | Evan D. Rosen | Ginger Kanzer-Lewis | Greg Milliger | Kristina Sandstedt | Laura Plunkett | Leonard Lipson, M.A. | Louis H. Philipson | Maria Emanuel Ryan, DDS, PhD | Marilyn Porter, RD, CDE | Melissa Diane Smith | Michael R. Cohen, RPh, MS, ScD, FASHP | Paul Chous, M.A., OD | Philip A. Wood PhD | R. Keith Campbell, Professor, B.Pharm, MBA, CDE | Sheri R. Colberg PhD | Sherri Shafer | Stanley Schwartz, MD, FACP, FACE | Steve Pohlit | Steven V. Edelman, M.D. | Timothy S. Hollingshead |
Cast Your Vote
Was the data release from CMS on Medicare payments a good idea?
CME/CE of the Week
Presented by CardioCareLive
Category: Cardiology



Search Articles On Diabetes In Control