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Letter From The Editor

This week there is a wealth of information on new drugs for diabetes and weight loss; see FDA Approves Eli Lilly Diabetes Combo Drug Jentadueto, Efficacy and Safety of Bydureon Versus Metformin, Pioglitazone, and Sitagliptin as Monotherapy, and Obesity Drug to Get Broader Label. New research also shows how chemical deficiencies, Effect of Sitagliptin on Serum Total Ghrelin Levels in Type 2's, or genetic mutations, Gene Study Sheds Light on Body Clock's Link to Diabetes, may affect the development and control of diabetes.

Results were also released from the Diabetes Excess Weight Loss (DEWL) Trial showing an equivalent modest weight loss on what the authors stated was either a low carb (40% of calories) or high carb diet (55% of calories). Although those numbers seem real, note that most other low carb diets are more in the 20-25% range and that may account for the reason that the weight loss was equivalent and A1c's did not decrease. The more important information from the study was that there was no difference in body fatness, lipids, blood pressure and renal function using a lower carb diet.

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Announcements:

TCOYD Conference and Health Fair, Walter E. Washington Convention Center, Washington, DC, Saturday, February 11, 2012

Join Steven Edelman, MD and Special Guest, Urban Miyares (Blinded Veteran, Entrepreneur, Motivational Speaker) for a day focused on diabetes education, health and wellness.

Please answer this week's poll: Do your type 2 patients not on insulin count their carbs and report back to you?

Vote in and then see results from previous polls here.

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We can make a difference!
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Check out this week's SPECIAL FEATURE GLP-1 "Test Your Diabetes Knowledge" question!

Dave Joffe, Editor-in-chiefRead More

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Newsflash

FDA Approves Second New Diabetes Drug within Three Days

Bydureon was the first to be approved, now find out what the second new drug is. (See this week's Item #3.)




Product of the Week

Nike Fuel Band: Tracks All Physical Activities

altNike has unveiled the Nike+ FuelBand, a product that fits around your wrist and aims to provide a common metric for tracking all physical activities. The FuelBand tracks what the company calls NikeFuel, which lets people compare a game of basketball to a dance class, for example. The band itself tracks activity through oxygen kinetics, which helps it determine whether a user is engaged in an intense sporting activity or sitting at a desk. Nike believes this will provide more precise measurement than simply tracking steps, and allow it to account for the differences across various sports (the device also tracks steps, calories, and time, however).

 

SPECIAL FEATURE: GLP-1 TEST YOUR KNOWLEDGE, Part 1

Scott is a 57-year-old white male who has been diagnosed with type 2 diabetes mellitus (T2DM) for 4 years. Upon diagnosis, with a glycosylated hemoglobin (A1c) level of 7.3%, he was initiated on lifestyle modifications plus metformin 500 mg twice daily. Eventually his metformin was titrated up to 1000 mg twice daily. After his best attempts at diet, exercise, and adherence to metformin for 1 year, his A1c was down to 6.4%. Scott presents to you most recently, however, with a loss of glycemic control despite continued best efforts on his part. His A1c has climbed to 7.7%, and you decide it is time to initiate another antihyperglycemic agent in addition to his metformin. At this visit his body mass index is 32 kg/m2, and his waist circumference is 46 inches.

Question 1: Which of the following represents the best choice as a next step for this patient, especially according to the American Association of Clinical Endocrinologists/American College of Endocrinology (AACE/ACE) algorithm for treatment of T2DM?...For the complete question and answer just follow this link.

 

Diabetes In Control Has Over 10000 Studies & Articles In Our Archives

Quote of the Week!

"For every failure, there's an alternative course of action. You just have to find it. When you come to a roadblock, take a detour."

               ...............Mary Kay Ash

 
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