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Impact of Physical Activity and Metformin on Postprandial Glucose

Oct 31, 2020
 
Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Tarshay Boyd, PharmD. Candidate, LECOM School of Pharmacy

Lifestyle modifications as first-line treatment have paramount importance in the quality of life. 

The first-line treatment for controlling diabetes starts with lifestyle modifications, including diet, exercise, and weight control. Lifestyle interventions can reduce risk factors for macrovascular and microvascular comorbidities of diabetes. The purpose of this study was to assess the interface of physical activity and metformin as it relates to postprandial glucose in glucose-intolerant people. Studies reported preventing the progression of prediabetes from type 2 diabetes with lifestyle modifications. One study reported a 58% reduction in type 2 diabetes with lifestyle intervention, compared to metformin treatment showing a 31% reduction. However, there have been different outcomes seen with physical activity and metformin for glucose control....

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