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Hybrid Closed-Loop Insulin Delivery for Children

Nov 10, 2020
Editor: Steve Freed, R.PH., CDE

Author: Zahra Hashemy, PharmD. Candidate, USF Taneja College of Pharmacy 

Young children with type 1 diabetes often experience greater insulin variability, leading to more complications and a subpar quality of life. 

Age can play a significant factor in insulin variability. Children's activities, developmental and hormonal changes can cause challenges with delivering insulin based on treatment goals. Hybrid closed-loop devices are a step above continuous injections and monitoring devices that need the user to determine the amount of insulin needed to be delivered at each delivery. Hybrid closed-loop devices deliver insulin autonomously by using an algorithm that sensors glucose values in real-time; standard delivery by the user is only given for boluses at the time of a meal.  

This study aims to determine the relationship between insulin variability and age, which has yet to be determined. Investigators sought to observe if insulin variability was higher amongst the younger population....

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