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INOSITOL
Physiology
and Clinical Effects
Inositol is required for proper formation of cell membranes. It affects
nerve transmission and helps in transporting fats within the body.
Food
Sources
Nuts, beans, wheat and wheat bran, cantaloupe, and oranges are excellent
sources of inositol. Most dietary inositol is in the form of phytate.
Deficiency
Risk and Symptoms
Clear deficiency of inositol has not been reported, although diabetics
have increased excretion and may benefit from inositol supplementation.
Recommended
Dosage
Most people do not need to take inositol. In addition, the small amounts
commonly found in multi-vitamin supplements are probably unnecessary and
ineffective. Doctors sometimes suggest 500 mg BID.
Contraindications
Toxicity has not been reported, although people with chronic renal failure
show elevated levels.
Large amounts
of phytate, the common dietary form of inositol, reduce the absorption of
calcium, iron, and zinc. However, supplemental inositol does not have this
effect.
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