Sunday , November 19 2017
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Granulox for Chronic Diabetic Foot Ulcers

Topical spray shows significant slough reduction and rapid wound healing.

Chronic diabetic foot ulcerations are very difficult to prevent and manage due to the complexity of the disease itself. For patients with chronic diabetic foot ulcers due to circulatory oxygen-deficient circumstances, innovative oxygen therapy can be an effective treatment.

Researchers conducted a study with 20 patients who had non-healing diabetic foot ulcerations that were not healed for 12 or more weeks. All wounds were treated with Granulox on eight set occasions for over a 4-week period.

Within four weeks, the average wound size reduction for all patients was 62% and even wounds that had been present for 12 months or more were reduced by an average of 24%. All patients also had wound slough between 10%-100% before using Granulox, but by week four of treatment all wounds were slough-free with no debridement required during treatment. There was also a significant reduction in exudate levels for all patients with a 29% reduction in wounds with mild exudate, an 86% reduction in moderate exuding wounds, and a complete resolution of all six patients with severely exuding wounds. There were no adverse events associated with the treatment and all the patients found the product acceptable and easy to use.

This study demonstrates that Granulox can promote rapid and complete wound closure and is an effective new treatment option for the management of foot ulcers in patients with diabetes.

Practice Pearls

  • Granulox is a topical spray solution containing purified hemoglobin which has the potential to substantially speed wound healing for patients with chronic diabetic foot ulcerations. The active hemoglobin improves oxygen supply to chronic wounds by increasing the diffusion of oxygen into the wound base which accelerates rapid healing.
  • Within four weeks, the average wound size reduction for all patients was 62% and even wounds which had been present for 12 months or more were reduced by an average of 24%.
  • This study demonstrates that Granulox can promote rapid and complete wound closure and is an effective new treatment option for the management of foot ulcers in patients with diabetes.

Bateman SD. Topical haemoglobin spray for diabetic foot ulceration. Br J Nurs. 2015.