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Glitzones May Be Linked to Eye Problems

Dec 20, 2005

European regulators said they were reviewing the safety of two popular oral diabetes drugs, Actos and Avandia following rare case of eye problems that may be associated with the medicines.

The European Medicines Agency said yesterday rare episodes of macular oedema, or swelling of the back of the eye, had been reported with GlaxoSmithKline Plc’s Avandia and Takeda Pharmaceutical Co Ltd’s Actos.

The agency’s Committee for Medicinal Products for Human Use will now carry out a review to establish whether there is a link between macular oedema and the use of the drugs, which belong to a class of diabetes treatments known as glitazones.

The medicines work by making the body’s cells more sensitive to insulin, thereby helping people with type II, or adult-onset, diabetes to better use their own natural insulin.


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