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FDA Approves New Sugar Substitute Advantame

A high-intensity sweetener developed by Japanese food and chemical corporation, Ajinomoto, Advantame is about 20,000 times sweeter than sucrose….

The FDA has approved Advantame for general use in foods and beverages. Advantame is also FEMA GRAS approved in Dairy, Frozen Desserts, Beverages, and Chewing Gum. Advantame is the sixth artificial sweetener to be approved by the FDA and is a white powder derived from aspartame and vanillin that dissolves in water, and continues to remain stable in high temperatures. Advantame’s structure is chemically similar to aspartame, and it was assumed a warning label notifying people with phenylketonuria (PKU) to the presence of phenylalanine was required, but after further evaluation the agency determined that, since advantame is approximately 100 times sweeter than aspartame and requires only a fraction of the amount to achieve the same degree of sweetness, no warning label is necessary. The director of the FDA’s Division of Petition Review and the US Public Health Service, Captain Andrew Zajac, stated "Sugar substitutes are called ‘high intensity’ because small amounts pack a large punch when it comes to sweetness." It is understood that artificial high-intensity sweeteners add little or no calories to a diet, and usually do not raise blood glucose levels in patients.

Advantame received consent to be used as a tabletop sweetener or as an ingredient for cooking purposes. Additionally, it can be used in a variety of foods including: baked goods, chewing gum, syrups, toppings, nonalcoholic beverages, frostings and confections, frozen desserts, puddings and gelatins, jellies and jams, fruit juices, and processed fruits. Research was designed to identify any harmful effects of the sweetener. In regards to, its effect on the immune, reproductive, developmental, and nervous system. The FDA based its approval on the results of 37 human and animal studies submitted by the manufacturer. Within the next few years advantame is expected to hit the US market.

Practice Pearls:
  • It is the sixth artificial sweetener to be approved from the FDA
  • The FDA based its approval on the results of 37 human and animal studies submitted by the manufacturer
  • Within the next few years advantame is expected to hit the US market

http://www.fda.gov/forconsumers/consumerupdates/ucm397711.htm