FDA Approves a Triple Therapy for Type 2 Diabetes in One Tablet

Feb 4, 2020

Editor: Steve Freed, R.PH., CDE

Author: George McConnell, PharmD. Candidate, LECOM School of Pharmacy

A few days ago, the FDA approved Trijardy XR. A combination of three, previously approved medications, Trijardy XR combines empagliflozin, linagliptin, and metformin hydrochloride extended-release. Empagliflozin, a sodium-glucose co-transporter 2 (SGLT-2) inhibitor, linagliptin, a dipeptidyl peptidase-4 (DPP4) inhibitor, and metformin hydrochloride, a biguanide, are all agents used to treat type 2 diabetes. The advantage of combining these agents is that they each have a different mechanism of action, so they lower blood glucose in different ways....

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