Elderly Women and the Risk of Breast Cancer When Initiating Certain Insulins

Apr 18, 2020

Editor: David L. Joffe, BSPharm, CDE, FACA

Author: Deonna Andrews, PharmD Candidate 2020 of Florida Agricultural & Mechanical University College of Pharmacy and Pharmaceutical Sciences

Insulin has changed the game in managing people with diabetes but has the potential to cause unwanted severe adverse effects in women 65 years of age and older.

Designed to overcome the limitations of neutral protamine Hagedorn insulin, long-acting insulin analogs such as glargine and detemir have become novel treatments in the management of chronic disease, diabetes. These structurally altered human insulins are thought to influence mitogenicity, which raised concerns in scientists about the potential glargine had to be carcinogenic....

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